Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
RYR2 Q92736 ryanodine receptor 2 Ion channel 1.00 0.539 0.615 16 95
GCH1 P30793 GTP cyclohydrolase 1 Enzyme 0.90 0.511 0.846 36 61
HADHA P40939 hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha Enzyme 4.4E-06 0.569 0.769 15 57
TNNT2 P45379 troponin T2, cardiac type Cellular structure 2.0E-03 0.601 0.423 41 55
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 130 54
PRKCE Q02156 protein kinase C epsilon Kinase 1.00 0.597 0.692 35 50
PDHA1 P08559 pyruvate dehydrogenase E1 subunit alpha 1 0.99 0.581 0.538 23 45
TUBA1A Q71U36 tubulin alpha 1a Cellular structure 0.97 0.597 0.769 9 44
ELN P15502 elastin 2.1E-14 0.415 0.885 24 42
TCF7L2 Q9NQB0 transcription factor 7 like 2 1.00 0.485 0.846 29 40
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 48 35
PGM1 P36871 phosphoglucomutase 1 5.1E-15 0.628 0.577 13 35
TFRC P02786 transferrin receptor Enzyme 7.0E-05 0.437 0.885 52 33
CD36 P16671 CD36 molecule Receptor 1.1E-60 0.446 0.846 19 31
GHR P10912 growth hormone receptor Signaling 8.4E-05 0.490 0.846 10 31
PDE4B Q07343 phosphodiesterase 4B 0.47 0.566 0.731 25 26
GATM P50440 glycine amidinotransferase 5.1E-02 0.666 0.615 18 23
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 53 22
KITLG P21583 KIT ligand 0.85 0.473 0.885 27 20
CTSC P53634 cathepsin C Enzyme 1.1E-07 0.541 0.731 16 20
IFNGR1 P15260 interferon gamma receptor 1 Receptor 1.6E-02 0.529 0.692 14 19
SLC8A1 P32418 solute carrier family 8 member A1 Transporter 1.00 0.544 0.769 36 18
AXIN2 Q9Y2T1 axin 2 0.57 0.507 0.692 20 18
EGR2 P11161 early growth response 2 Nucleic acid binding 0.50 0.547 0.769 14 18