Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692 18
ACADVL P49748 acyl-CoA dehydrogenase very long chain Enzyme 4.2E-15 0.653 0.654 6
ALDOA P04075 aldolase, fructose-bisphosphate A 1.3E-03 0.631 0.615 3
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 32
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885 16
APOC3 P02656 apolipoprotein C3 1.0E-02 0.531 0.731 6
ATP12A P54707 ATPase H+/K+ transporting non-gastric alpha2 subunit Transporter 7.1E-14 0.575 0.769 2
ATP2A2 P16615 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Transporter 1.00 0.529 0.808 15
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 62
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 44
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 40
CD36 P16671 CD36 molecule Receptor 1.1E-60 0.446 0.846 20
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808 4
CYBA P13498 cytochrome b-245 alpha chain 8.9E-06 0.520 0.769 10
EPHX2 P34913 epoxide hydrolase 2 Enzyme 1.8E-21 0.568 0.654 7
FADD Q13158 Fas associated via death domain 0.53 0.537 0.846 14
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 49
FGF19 O95750 fibroblast growth factor 19 Signaling 0.57 0.548 0.615 9
G6PD P11413 glucose-6-phosphate dehydrogenase Enzyme 0.97 0.424 0.846 32
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885 30
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 71
HDAC3 O15379 histone deacetylase 3 Epigenetic regulator 0.57 0.511 0.731 6
HSD11B1 P28845 hydroxysteroid 11-beta dehydrogenase 1 0.42 0.520 0.731 8
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885 28