Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962 805 74
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923 565 23
DMD P11532 dystrophin 1.00 0.423 0.923 484 345
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923 469 292
FHIT P49789 fragile histidine triad diadenosine triphosphatase 5.7E-03 0.444 0.846 337 33
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 321 71
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808 319 157
DCC P43146 DCC netrin 1 receptor 0.99 0.471 0.808 279 101
LINC01672 long intergenic non-protein coding RNA 1672 0.462 0.846 268 0
MUL1 Q969V5 mitochondrial E3 ubiquitin protein ligase 1 1.9E-06 0.473 0.808 241 8
DDC P20711 dopa decarboxylase 3.8E-08 0.535 0.769 164 68
ATP13A2 Q9NQ11 ATPase cation transporting 13A2 9.0E-09 0.566 0.577 160 31
PODXL O00592 podocalyxin like 1.0E-03 0.551 0.731 156 5
HTRA2 O43464 HtrA serine peptidase 2 3.6E-03 0.542 0.692 151 6
DNAJC6 O75061 DnaJ heat shock protein family (Hsp40) member C6 1.00 0.641 0.385 86 10
FBXO7 Q9Y3I1 F-box protein 7 5.8E-07 0.650 0.769 76 51
UBE2K P61086 ubiquitin conjugating enzyme E2 K 0.99 0.631 0.654 58 0
SKIL P12757 SKI like proto-oncogene 0.99 0.621 0.538 58 1
RNF41 Q9H4P4 ring finger protein 41 0.97 0.674 0.538 40 0
CNTN5 O94779 contactin 5 6.2E-05 0.695 0.462 34 20
UBE2E2 Q96LR5 ubiquitin conjugating enzyme E2 E2 0.96 0.695 0.423 30 64
PACRG Q96M98 parkin coregulated 2.4E-07 0.722 0.308 19 6
FRA6E fragile site, aphidicolin type, common, fra(6)(q26) 0.792 0.231 13 0
PTRHD1 Q6GMV3 peptidyl-tRNA hydrolase domain containing 1 4.6E-07 0.890 0.154 5 2