Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962 2494 527
ALB P02768 albumin Transporter 0.64 0.317 0.962 1198 21
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885 852 81
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962 805 74
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 668 32
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885 616 11
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923 565 23
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885 506 3
DMD P11532 dystrophin 1.00 0.423 0.923 484 345
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923 469 292
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846 462 173
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885 449 66
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846 437 42
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923 434 107
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846 409 88
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885 409 13
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808 356 58
LTA P01374 lymphotoxin alpha Signaling 0.20 0.434 0.885 353 26
FHIT P49789 fragile histidine triad diadenosine triphosphatase 5.7E-03 0.444 0.846 337 33
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 321 71
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808 319 157
PRKCD Q05655 protein kinase C delta Kinase 1.00 0.480 0.846 287 4
DCC P43146 DCC netrin 1 receptor 0.99 0.471 0.808 279 101
ALDH1A1 P00352 aldehyde dehydrogenase 1 family member A1 Enzyme 0.95 0.460 0.846 270 7