Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PRMT3 O60678 protein arginine methyltransferase 3 Epigenetic regulator 4.9E-25 0.743 0.423 1
C5 P01031 complement C5 Enzyme modulator 8.1E-24 0.550 0.731 8
SLC22A1 O15245 solute carrier family 22 member 1 Transporter 1.5E-22 0.556 0.731 6
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 43
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 59
FGA P02671 fibrinogen alpha chain 1.2E-13 0.573 0.769 14
CHAT P28329 choline O-acetyltransferase Enzyme 5.6E-11 0.520 0.808 2
C3AR1 Q16581 complement C3a receptor 1 G-protein coupled receptor 3.3E-09 0.601 0.731 4
MUC5AC P98088 mucin 5AC, oligomeric mucus/gel-forming Enzyme modulator 1.0E-08 0.483 0.808 10
LTA4H P09960 leukotriene A4 hydrolase 3.0E-08 0.617 0.654 4
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 25
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923 10
TLR3 O15455 toll like receptor 3 Receptor 1.6E-07 0.427 0.885 8
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808 11
PRF1 P14222 perforin 1 5.5E-06 0.540 0.692 4
F7 P08709 coagulation factor VII Enzyme 1.3E-05 0.623 0.615 16
PLA2G4A P47712 phospholipase A2 group IVA Enzyme 6.0E-05 0.496 0.846 16
SFTPD P35247 surfactant protein D Surfactant 7.5E-05 0.500 0.846 9
CCR3 P51677 C-C motif chemokine receptor 3 G-protein coupled receptor 1.3E-04 0.527 0.808 3
CCL17 Q92583 C-C motif chemokine ligand 17 Signaling 1.4E-04 0.518 0.808 5
IL22 Q9GZX6 interleukin 22 1.9E-04 0.393 0.885 4
SFTPB P07988 surfactant protein B 2.6E-04 0.575 0.654 6
SFTPA1 Q8IWL2 surfactant protein A1 3.7E-04 0.546 0.808 6