Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
PLCE1 Q9P212 phospholipase C epsilon 1 Enzyme 5.7E-11 0.572 0.654 16 44
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 138 40
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 83 37
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846 30 36
RORA P35398 RAR related orphan receptor A Nuclear receptor 0.40 0.533 0.808 10 36
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 164 35
CTNNA1 P35221 catenin alpha 1 Cellular structure 0.97 0.584 0.538 16 35
FADS1 O60427 fatty acid desaturase 1 0.37 0.582 0.769 11 32
ALDH7A1 P49419 aldehyde dehydrogenase 7 family member A1 Enzyme 1.4E-22 0.551 0.769 8 32
CTNNA2 P26232 catenin alpha 2 Cellular structure 0.43 0.663 0.500 11 31
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 92 30
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923 43 30
RARB P10826 retinoic acid receptor beta Nuclear receptor 1.00 0.478 0.846 37 30
FHIT P49789 fragile histidine triad diadenosine triphosphatase 5.7E-03 0.444 0.846 32 29
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846 90 28
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808 60 28
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846 25 28
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808 47 26
ECHS1 P30084 enoyl-CoA hydratase, short chain 1 Enzyme 8.8E-04 0.601 0.654 15 26
IL6R P08887 interleukin 6 receptor Signaling 3.2E-05 0.471 0.846 21 25
ZBTB20 Q9HC78 zinc finger and BTB domain containing 20 0.97 0.566 0.731 8 25
DNMT3B Q9UBC3 DNA methyltransferase 3 beta 0.20 0.453 0.846 27 23
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 120 21
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885 59 21