Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
MMP8 P22894 matrix metallopeptidase 8 Enzyme 1.1E-24 0.488 0.808 12
SYNM O15061 synemin 3.0E-24 0.575 0.731 2
SLCO1B3 Q9NPD5 solute carrier organic anion transporter family member 1B3 Transporter 5.3E-24 0.592 0.769 5
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885 17
NOTCH4 Q99466 notch receptor 4 2.1E-23 0.534 0.731 6
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846 14
GPT P24298 glutamic--pyruvic transaminase Enzyme 3.6E-19 0.403 0.923 8
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885 48
CFAP52 Q8N1V2 cilia and flagella associated protein 52 8.1E-18 0.890 0.154 1
PER3 P56645 period circadian regulator 3 Transcription factor 1.4E-17 0.559 0.731 3
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 149
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 27
SERPINB4 P48594 serpin family B member 4 Enzyme modulator 8.8E-17 0.623 0.423 7
GJB2 P29033 gap junction protein beta 2 Cell-cell junction 6.6E-16 0.441 0.846 22
ROBO1 Q9Y6N7 roundabout guidance receptor 1 7.3E-16 0.535 0.731 6
SERPINB3 P29508 serpin family B member 3 Enzyme modulator 8.2E-16 0.565 0.615 8
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808 13
SULT2A1 Q06520 sulfotransferase family 2A member 1 1.3E-15 0.545 0.769 3
AKR1C1 Q04828 aldo-keto reductase family 1 member C1 Enzyme 3.5E-15 0.593 0.615 5
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 67
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885 52
ASPH Q12797 aspartate beta-hydroxylase 6.6E-15 0.610 0.615 7
SLC25A47 Q6Q0C1 solute carrier family 25 member 47 Transporter 8.2E-15 0.839 0.077 1
MTRR Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.2E-14 0.502 0.808 19