Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
LMNA P02545 lamin A/C 1.00 0.384 0.885 824 285
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 816 64
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 703 97
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 662 37
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923 602 66
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885 589 19
FLNA P21333 filamin A 1.00 0.419 0.846 571 85
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846 452 109
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808 443 59
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808 423 21
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846 400 73
GJB2 P29033 gap junction protein beta 2 Cell-cell junction 6.6E-16 0.441 0.846 392 132
GLI1 P08151 GLI family zinc finger 1 7.7E-14 0.431 0.846 369 14
SRY Q05066 sex determining region Y Transcription factor 0.456 0.808 315 27
GPC3 P51654 glypican 3 1.00 0.466 0.808 311 16
ABCA1 O95477 ATP binding cassette subfamily A member 1 Transporter 1.5E-13 0.467 0.846 291 116
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846 270 90
SOST Q9BQB4 sclerostin 0.87 0.474 0.808 270 4
ZMPSTE24 O75844 zinc metallopeptidase STE24 Enzyme 8.9E-16 0.517 0.731 265 11
IKBKG Q9Y6K9 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Kinase 8.5E-02 0.493 0.769 252 32
SMC1A Q14683 structural maintenance of chromosomes 1A 1.00 0.509 0.808 251 53
STIM1 Q13586 stromal interaction molecule 1 0.78 0.501 0.808 247 23
SATB2 Q9UPW6 SATB homeobox 2 Transcription factor 1.00 0.503 0.769 233 38
TBC1D24 Q9ULP9 TBC1 domain family member 24 Enzyme modulator 1.3E-08 0.530 0.808 218 39