Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
LMNA P02545 lamin A/C 1.00 0.384 0.885 824 285
FLNA P21333 filamin A 1.00 0.419 0.846 571 85
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846 400 73
GLI1 P08151 GLI family zinc finger 1 7.7E-14 0.431 0.846 369 14
GPC3 P51654 glypican 3 1.00 0.466 0.808 311 16
SOST Q9BQB4 sclerostin 0.87 0.474 0.808 270 4
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846 270 90
SMC1A Q14683 structural maintenance of chromosomes 1A 1.00 0.509 0.808 251 53
STIM1 Q13586 stromal interaction molecule 1 0.78 0.501 0.808 247 23
KRT5 P13647 keratin 5 0.64 0.512 0.731 203 58
NECTIN1 Q15223 nectin cell adhesion molecule 1 6.1E-02 0.523 0.808 196 5
WDR35 Q9P2L0 WD repeat domain 35 1.0E-22 0.525 0.692 188 30
GPC4 O75487 glypican 4 0.93 0.547 0.769 181 8
KRT14 P02533 keratin 14 2.0E-04 0.530 0.731 173 47
TINF2 Q9BSI4 TERF1 interacting nuclear factor 2 1.3E-03 0.575 0.731 158 20
LRP4 O75096 LDL receptor related protein 4 1.4E-06 0.568 0.692 151 23
KRT17 Q04695 keratin 17 1.1E-11 0.531 0.654 140 14
COL17A1 Q9UMD9 collagen type XVII alpha 1 chain 2.3E-27 0.545 0.769 138 28
ITGA6 P23229 integrin subunit alpha 6 1.9E-07 0.539 0.769 137 7
TRRAP Q9Y4A5 transformation/transcription domain associated protein 1.00 0.572 0.692 122 10
CTC1 Q2NKJ3 CST telomere replication complex component 1 1.6E-11 0.601 0.538 121 24
EVC2 Q86UK5 EvC ciliary complex subunit 2 1.0E-34 0.585 0.692 106 75
EVC P57679 EvC ciliary complex subunit 1 3.5E-25 0.587 0.577 104 65
WRAP53 Q9BUR4 WD repeat containing antisense to TP53 5.4E-05 0.603 0.692 103 11