Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Cluster analysis of mRNA expression levels identifies multiple sequential patterns following focal cerebral ischemia. 22843461

2012

Entrez Id: 2243
Gene Symbol: FGA
FGA
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Therapeutic RGD [Protective effects and anticoagulation effect of polysaccharides from the sea cucumber on acute incomplete cerebral ischemia in rats]. 22737923

2012

Entrez Id: 572
Gene Symbol: BAD
BAD
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Cluster analysis of mRNA expression levels identifies multiple sequential patterns following focal cerebral ischemia. 22843461

2012

Entrez Id: 4133
Gene Symbol: MAP2
MAP2
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Microtubule-associated protein 2, an early blood marker of ischemic brain injury. 21948028

2012

Entrez Id: 3654
Gene Symbol: IRAK1
IRAK1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Interleukin-1 receptor associated kinases-1/4 inhibition protects against acute hypoxia/ischemia-induced neuronal injury in vivo and in vitro. 21925238

2011

Entrez Id: 9590
Gene Symbol: AKAP12
AKAP12
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Temporal profile of Src, SSeCKS, and angiogenic factors after focal cerebral ischemia: correlations with angiogenesis and cerebral edema. 21334414

2011

Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Tin chloride enhances parvalbumin-positive interneuron survival by modulating heme metabolism in a model of cerebral ischemia. 21276833

2011

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Nicotinamide attenuates the ischemic brain injury-induced decrease of Akt activation and Bad phosphorylation. 21596097

2011

Entrez Id: 51135
Gene Symbol: IRAK4
IRAK4
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Interleukin-1 receptor associated kinases-1/4 inhibition protects against acute hypoxia/ischemia-induced neuronal injury in vivo and in vitro. 21925238

2011

Entrez Id: 1464
Gene Symbol: CSPG4
CSPG4
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD The alterations of oligodendrocyte, myelin in corpus callosum, and cognitive dysfunction following chronic cerebral ischemia in rats. 21864831

2011

Entrez Id: 246
Gene Symbol: ALOX15
ALOX15
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Neuroprotection of early and short-time applying atorvastatin in the acute phase of cerebral ischemia: down-regulated 12/15-LOX, p38MAPK and cPLA2 expression, ameliorated BBB permeability. 20167207

2010

Entrez Id: 3976
Gene Symbol: LIF
LIF
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD "TGFbeta1 stimulates the over-production of white matter astrocytes from precursors of the ""brain marrow"" in a rodent model of neonatal encephalopathy." 20221422

2010

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Regulation of endothelial nitric oxide synthase by agmatine after transient global cerebral ischemia in rat brain. 21212863

2010

Entrez Id: 1808
Gene Symbol: DPYSL2
DPYSL2
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Upregulation of Dpysl2 and Spna2 gene expression in the rat brain after ischemic stroke. 19524114

2009

Entrez Id: 2246
Gene Symbol: FGF1
FGF1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Protective effects of mutant of acidic fibroblast growth factor against cerebral ischaemia-reperfusion injury in rats. 19497570

2009

Entrez Id: 361
Gene Symbol: AQP4
AQP4
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Temporal changes in expression of aquaporin-3, -4, -5 and -8 in rat brains after permanent focal cerebral ischemia. 19616516

2009

Entrez Id: 343
Gene Symbol: AQP8
AQP8
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Temporal changes in expression of aquaporin-3, -4, -5 and -8 in rat brains after permanent focal cerebral ischemia. 19616516

2009

Entrez Id: 362
Gene Symbol: AQP5
AQP5
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Temporal changes in expression of aquaporin-3, -4, -5 and -8 in rat brains after permanent focal cerebral ischemia. 19616516

2009

Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Ionic mechanisms underlying action potential prolongation by focal cerebral ischemia in rat ventricular myocytes. 19471098

2009

Entrez Id: 3791
Gene Symbol: KDR
KDR
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Attenuation of edema and infarct volume following focal cerebral ischemia by early but not delayed administration of a novel small molecule KDR kinase inhibitor. 18951929

2009

Entrez Id: 360
Gene Symbol: AQP3
AQP3
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Our findings indicated that dynamic changes of AQP3, -4, -5 and -8 expression could contribute to the development of cerebral edema after brain ischemia. 19616516

2009

Entrez Id: 7082
Gene Symbol: TJP1
TJP1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Matrix metalloproteinases inhibition provides neuroprotection against hypoxia-ischemia in the developing brain. 19712057

2009

Entrez Id: 2021
Gene Symbol: ENDOG
ENDOG
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Endonuclease G expression in thalamic reticular nucleus after global cerebral ischemia. 18568342

2008

Entrez Id: 7054
Gene Symbol: TH
TH
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Selective losses of brainstem catecholamine neurons after hypoxia-ischemia in the immature rat pup. 18356740

2008

Entrez Id: 572
Gene Symbol: BAD
BAD
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Melatonin attenuates the focal cerebral ischemic injury by inhibiting the dissociation of pBad from 14-3-3. 18078455

2008