Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4899
Gene Symbol: NRF1
NRF1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Rapidly increased neuronal mitochondrial biogenesis after hypoxic-ischemic brain injury. 18723421

2008

Entrez Id: 1356
Gene Symbol: CP
CP
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD An inhibition of ceruloplasmin expression induced by cerebral ischemia in the cortex and hippocampus of rats. 18273071

2008

Entrez Id: 8165
Gene Symbol: AKAP1
AKAP1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Proteolysis of AKAP121 regulates mitochondrial activity during cellular hypoxia and brain ischaemia. 18323779

2008

Entrez Id: 356
Gene Symbol: FASLG
FASLG
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD FasL shedding is reduced by hypothermia in experimental stroke. 18410517

2008

Entrez Id: 1621
Gene Symbol: DBH
DBH
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Selective losses of brainstem catecholamine neurons after hypoxia-ischemia in the immature rat pup. 18356740

2008

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD The protective effect of dexanabinol (HU-211) on nitric oxide and cysteine protease-mediated neuronal death in focal cerebral ischemia. 18404379

2008

Entrez Id: 1514
Gene Symbol: CTSL
CTSL
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD The protective effect of dexanabinol (HU-211) on nitric oxide and cysteine protease-mediated neuronal death in focal cerebral ischemia. 18404379

2008

Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD DeltaPKC mediates microcerebrovascular dysfunction in acute ischemia and in chronic hypertensive stress in vivo. 17350602

2007

Entrez Id: 9510
Gene Symbol: ADAMTS1
ADAMTS1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD The quantification of ADAMTS expression in an animal model of cerebral ischemia using real-time PCR. 17073862

2007

Entrez Id: 317
Gene Symbol: APAF1
APAF1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Greater stress protein expression enhanced by combined prostaglandin A1 and lithium in a rat model of focal ischemia. 17640469

2007

Entrez Id: 5058
Gene Symbol: PAK1
PAK1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD A microarray study of gene and protein regulation in human and rat brain following middle cerebral artery occlusion. 17997827

2007

Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD A high soy diet reduces programmed cell death and enhances bcl-xL expression in experimental stroke. 17706879

2007

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Resveratrol neuroprotective effects during focal cerebral ischemia injury via nitric oxide mechanism in rats. 17600658

2007

Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Glucocorticoid receptor expression in the cortex of the neonatal rat brain with and without focal cerebral ischemia. 17344647

2007

Entrez Id: 10763
Gene Symbol: NES
NES
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD [Neuroprotective effects of exogenous basic fibroblast growth factor on the hypoxic-ischemic brain damage of neonatal rats]. 17697621

2007

Entrez Id: 7432
Gene Symbol: VIP
VIP
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD VIP injection can reduce the infarct volume in rats with focal cerebral ischemia, suggesting the neuroprotective effect of VIP in brain ischemia possibly by reducing S100beta overexpression. 18158987

2007

Entrez Id: 831
Gene Symbol: CAST
CAST
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD 3-[2-[4-(3-Chloro-2-methylphenylmethyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydro-chloride 3.5 hydrate (DY-9760e) is neuroprotective in rat microsphere embolism: role of the cross-talk between calpain and caspase-3 through calpastatin. 16467455

2006

Entrez Id: 3312
Gene Symbol: HSPA8
HSPA8
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Irreversible aggregation of protein synthesis machinery after focal brain ischemia. 16805800

2006

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD The physiopathology of the brain ischemia includes many events such as important apoptotic mechanisms were Fas protein is expressed. 16796407

2006

Entrez Id: 857
Gene Symbol: CAV1
CAV1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Nitric oxide down-regulates caveolin-1 expression in rat brains during focal cerebral ischemia and reperfusion injury. 16417587

2006

Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Expression of heme oxygenase-1 protein and messenger RNA in permanent cerebral ischemia in rats. 16464361

2006

Entrez Id: 10370
Gene Symbol: CITED2
CITED2
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Induction of CITED2 expression in the rat hippocampus following transient global ischemia. 16434029

2006

Entrez Id: 5740
Gene Symbol: PTGIS
PTGIS
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Induction of prostacyclin/PGI2 synthase expression after cerebral ischemia-reperfusion. 16094316

2006

Entrez Id: 51083
Gene Symbol: GAL
GAL
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Specific expression of galanin in the peri-infarct zone after permanent focal cerebral ischemia in the rat. 16458372

2006

Entrez Id: 5599
Gene Symbol: MAPK8
MAPK8
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD Neuroprotective effects of preconditioning ischemia on ischemic brain injury through down-regulating activation of JNK1/2 via N-methyl-D-aspartate receptor-mediated Akt1 activation. 15797868

2005