×
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
Cardiomegaly
0.510
Therapeutic
RGD
Curcumin inhibits cardiac hypertrophy and improves cardiovascular function via enhanced Na
29331788 2018
×
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
Cardiomegaly
0.510
Biomarker
RGD
Increased expression of endothelial nitric oxide synthase and caveolin-1 in the aorta of rats with isoproterenol-induced cardiac hypertrophy.
17487232 2006
×
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
Cardiomegaly
0.510
ModifyingMutation
RGD
Endothelin-1 and its binding sites are upregulated in pressure overload cardiac hypertrophy.
7771559 1995
×
Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2
Cardiomegaly
0.500
Therapeutic
RGD
Pharmacological inhibition of DNA methylation attenuates pressure overload-induced cardiac hypertrophy in rats.
29792884 2018
×
Entrez Id: 9927
Gene Symbol: MFN2
MFN2
Cardiomegaly
0.500
Therapeutic
RGD
Oleuropein improves mitochondrial function to attenuate oxidative stress by activating the Nrf2 pathway in the hypothalamic paraventricular nucleus of spontaneously hypertensive rats.
27847271 2017
×
Entrez Id: 9927
Gene Symbol: MFN2
MFN2
Cardiomegaly
0.500
Biomarker
RGD
Candesartan cilexetil attenuated cardiac remodeling by improving expression and function of mitofusin 2 in SHR.
27085127 2016
×
Entrez Id: 183
Gene Symbol: AGT
AGT
Cardiomegaly
0.500
Biomarker
RGD
Chronic infusion of enalaprilat into hypothalamic paraventricular nucleus attenuates angiotensin II-induced hypertension and cardiac hypertrophy by restoring neurotransmitters and cytokines.
24342267 2014
×
Entrez Id: 51548
Gene Symbol: SIRT6
SIRT6
Cardiomegaly
0.500
Biomarker
RGD
Sirtuin 6 protects cardiomyocytes from hypertrophy in vitro via inhibition of NF-κB-dependent transcriptional activity.
22335191 2013
×
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
Cardiomegaly
0.500
Therapeutic
RGD
[Effects of buyang huanwu decoction on the sarcoplasmic reticulum calcium uptake in abdominal aortic constriction induced myocardial hypertrophic rats].
23905381 2013
×
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
Cardiomegaly
0.500
Therapeutic
RGD
[Effects of buyang huanwu decoction on the sarcoplasmic reticulum calcium uptake in abdominal aortic constriction induced myocardial hypertrophic rats].
23905381 2013
×
Entrez Id: 183
Gene Symbol: AGT
AGT
Cardiomegaly
0.500
Biomarker
RGD
Angiotensin II increases periostin expression via Ras/p38 MAPK/CREB and ERK1/2/TGF-β1 pathways in cardiac fibroblasts.
21367774 2011
×
Entrez Id: 1545
Gene Symbol: CYP1B1
CYP1B1
Cardiomegaly
0.500
Therapeutic
RGD
Cytochrome P450 1B1 contributes to angiotensin II-induced hypertension and associated pathophysiology.
20805442 2010
×
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
Cardiomegaly
0.500
Biomarker
RGD
Anti-hypertrophic effect of NHE-1 inhibition involves GSK-3beta-dependent attenuation of mitochondrial dysfunction.
19318234 2009
×
Entrez Id: 2247
Gene Symbol: FGF2
FGF2
Cardiomegaly
0.500
Biomarker
RGD
Parallel up-regulation of FGF-2 and hyaluronan during development of cardiac hypertrophy in rat.
18196276 2008
×
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
Cardiomegaly
0.500
Biomarker
RGD
Parallel gene expressions of IL-6 and BNP during cardiac hypertrophy complicated with diastolic dysfunction in spontaneously hypertensive rats.
16762434 2007
×
Entrez Id: 857
Gene Symbol: CAV1
CAV1
Cardiomegaly
0.500
Biomarker
RGD
Increased expression of endothelial nitric oxide synthase and caveolin-1 in the aorta of rats with isoproterenol-induced cardiac hypertrophy.
17487232 2006
×
Entrez Id: 5578
Gene Symbol: PRKCA
PRKCA
Cardiomegaly
0.500
Biomarker
RGD
Protein kinase C isozymes in hypertension and hypertrophy: insight from SHHF rat hearts.
15792354 2005
×
Entrez Id: 5467
Gene Symbol: PPARD
PPARD
Cardiomegaly
0.500
Biomarker
RGD
Nuclear factor-kappaB activation leads to down-regulation of fatty acid oxidation during cardiac hypertrophy.
15728586 2005
×
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Cardiomegaly
0.500
Biomarker
RGD
Differential expression of cytokines in the rat heart in response to sustained volume overload.
15542404 2004
×
Entrez Id: 5579
Gene Symbol: PRKCB
PRKCB
Cardiomegaly
0.500
Biomarker
RGD
Differential induction of protein kinase C isoforms at the cardiac hypertrophy stage and congestive heart failure stage in Dahl salt-sensitive rats.
12887134 2003
×
Entrez Id: 9464
Gene Symbol: HAND2
HAND2
Cardiomegaly
0.500
Biomarker
RGD
HAND1 and HAND2 are expressed in the adult-rodent heart and are modulated during cardiac hypertrophy.
12359233 2002
×
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
Cardiomegaly
0.230
Biomarker
RGD
Angiotensin II increases periostin expression via Ras/p38 MAPK/CREB and ERK1/2/TGF-β1 pathways in cardiac fibroblasts.
21367774 2011
×
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
Cardiomegaly
0.230
Biomarker
RGD
[Dynamic changes of angiotensin II type-1 receptor mRNA expression in volume-overloaded ventricular hypertrophy].
11324571 1998
×
Entrez Id: 1636
Gene Symbol: ACE
ACE
Cardiomegaly
0.220
Therapeutic
RGD
Chronic infusion of enalaprilat into hypothalamic paraventricular nucleus attenuates angiotensin II-induced hypertension and cardiac hypertrophy by restoring neurotransmitters and cytokines.
24342267 2014
×
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
Cardiomegaly
0.210
Biomarker
RGD
Isorhapontigenin, a new resveratrol analog, attenuates cardiac hypertrophy via blocking signaling transduction pathways.
15607907 2005