×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Portal Hypertension
0.540
Biomarker
RGD
Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease.
26627607 2016
×
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
Portal Hypertension
0.510
Therapeutic
RGD
Post-Transcriptional Regulation of Hepatic DDAH1 with TNF Blockade Leads to Improved eNOS Function and Reduced Portal Pressure In Cirrhotic Rats.
29263339 2017
×
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
Portal Hypertension
0.510
Biomarker
RGD
A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension.
16142243 2005
×
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
Portal Hypertension
0.510
Biomarker
RGD
Role of aortic nitric oxide synthase 3 (eNOS) in the systemic vasodilation of portal hypertension.
10889169 2000
×
Entrez Id: 551
Gene Symbol: AVP
AVP
Portal Hypertension
0.500
Biomarker
RGD
Restriction of drinking water abrogates splanchnic vasodilation and portal hypertension in portal vein-ligated rats.
18987488 2009
×
Entrez Id: 2153
Gene Symbol: F5
F5
Portal Hypertension
0.300
Biomarker
RGD
Portal hypertension and ascites in acute hepatitis: clinical, hemodynamic and histological correlations.
2777210 1989
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Portal Hypertension
0.230
Biomarker
RGD
Tumor necrosis factor-alpha regulates inducible nitric oxide synthase gene expression in the portal hypertensive gastric mucosa of the rat.
9834372 2006
×
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
Portal Hypertension
0.230
Biomarker
RGD
Antioxidant role of heme oxygenase-1 in prehepatic portal hypertensive rats.
16830363 2006
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Portal Hypertension
0.230
Therapeutic
RGD
Factors mediating the hemodynamic effects of tumor necrosis factor-alpha in portal hypertensive rats.
10070045 1999
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Portal Hypertension
0.230
Therapeutic
RGD
Tumor necrosis factor alpha regulates nitric oxide synthase expression in portal hypertensive gastric mucosa of rats.
9537427 1998
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Portal Hypertension
0.230
Biomarker
RGD
Hyperdynamic circulation in prehepatic portal hypertension: role of tumor necrosis factor-alpha.
9198288 1997
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Portal Hypertension
0.230
Therapeutic
RGD
Tumor necrosis factor alpha: a major contributor to the hyperdynamic circulation in prehepatic portal-hypertensive rats.
7875478 1995
×
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
Portal Hypertension
0.220
Therapeutic
RGD
Bile-acid-activated farnesoid X receptor regulates hydrogen sulfide production and hepatic microcirculation.
19418582 2009
×
Entrez Id: 64506
Gene Symbol: CPEB1
CPEB1
Portal Hypertension
0.210
Biomarker
RGD
Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease.
26627607 2016
×
Entrez Id: 22846
Gene Symbol: VASH1
VASH1
Portal Hypertension
0.210
ModifyingMutation
RGD
Disruption of negative feedback loop between vasohibin-1 and vascular endothelial growth factor decreases portal pressure, angiogenesis, and fibrosis in cirrhotic rats.
24390792 2014
×
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
Portal Hypertension
0.210
Biomarker
RGD
Apelin signaling modulates splanchnic angiogenesis and portosystemic collateral vessel formation in rats with portal hypertension.
19070926 2009
×
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
Portal Hypertension
0.210
Biomarker
RGD
[Effect and mechanism of salvianolic acid B in attenuating elevated portal pressure in a rat model of portal hypertension induced by endothelin-1].
17214938 2007
×
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1
Portal Hypertension
0.210
Biomarker
RGD
Activation of eNOS in rat portal hypertensive gastric mucosa is mediated by TNF-alpha via the PI 3-kinase-Akt signaling pathway.
11826414 2002
×
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
Portal Hypertension
0.210
Therapeutic
RGD
Gene transfer of the neuronal NO synthase isoform to cirrhotic rat liver ameliorates portal hypertension.
10727442 2000
×
Entrez Id: 9572
Gene Symbol: NR1D1
NR1D1
Portal Hypertension
0.200
Therapeutic
RGD
Novel role of nuclear receptor Rev-erbα in hepatic stellate cell activation: potential therapeutic target for liver injury.
24497272 2014
×
Entrez Id: 156
Gene Symbol: GRK2
GRK2
Portal Hypertension
0.200
Therapeutic
RGD
Glytan decreases portal pressure via mesentery vasoconstriction in portal hypertensive rats.
25469036 2014
×
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
Portal Hypertension
0.200
Therapeutic
RGD
Rapamycin ameliorates inflammation and fibrosis in the early phase of cirrhotic portal hypertension in rats through inhibition of mTORC1 but not mTORC2.
24404143 2014
×
Entrez Id: 409
Gene Symbol: ARRB2
ARRB2
Portal Hypertension
0.200
Therapeutic
RGD
Reactive oxygen species are involved in regulating hypocontractility of mesenteric artery to norepinephrine in cirrhotic rats with portal hypertension.
24719556 2014
×
Entrez Id: 4804
Gene Symbol: NGFR
NGFR
Portal Hypertension
0.200
Biomarker
RGD
Blockage of the afferent sensitive pathway prevents sympathetic atrophy and hemodynamic alterations in rat portal hypertension.
22292477 2012
SERPINF1
Portal Hypertension
0.200
Biomarker
RGD
The expression of PEDF and VEGF in the gastric wall of prehepatic portal hypertensive rats.
22024088 2012