| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
prostaglandin I2 synthase | 0.617 | 0.654 | 1.2E-09 |
|
disease | 0.630 | limited | < 0.001 | 3 | 1 | 2001 | 2003 | ||||||||
|
angiotensinogen | 0.367 | 0.923 | 5.0E-08 |
|
disease | 0.600 | None | 0.932 | 146 | 3 | 1988 | 2020 | ||||||||
|
angiotensin II receptor type 1 | 0.423 | 0.846 | 5.3E-04 |
|
disease | 0.600 | None | 0.941 | 50 | 7 | 1994 | 2019 | ||||||||
|
nitric oxide synthase 3 | 0.378 | 0.885 | 6.7E-07 |
|
disease | 0.600 | None | 0.917 | 34 | 6 | 1995 | 2018 | ||||||||
|
adducin 1 | 0.612 | 0.615 | 0.99 |
|
disease | 0.400 | None | 0.944 | 36 | 4 | 1995 | 2017 | ||||||||
|
G protein subunit beta 3 | 0.518 | 0.808 | 3.3E-11 |
|
disease | 0.400 | None | 0.909 | 33 | 2 | 1998 | 2017 | ||||||||
|
nitric oxide synthase 2 | 0.364 | 0.923 | 4.0E-15 |
|
disease | 0.330 | None | 1.000 | 3 | 0 | 1997 | 2001 | ||||||||
|
regulator of G protein signaling 5 | 0.647 | 0.423 | 5.3E-04 |
|
disease | 0.320 | None | 1.000 | 2 | 1 | 2009 | 2015 | ||||||||
|
endothelin converting enzyme 1 | 0.541 | 0.769 | 0.96 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2007 | 2007 | ||||||||
|
ATPase Na+/K+ transporting subunit beta 1 | 0.700 | 0.462 | 1.00 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2009 | 2009 | ||||||||
|
uromodulin | 0.520 | 0.846 | 3.1E-17 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2014 | 2014 | ||||||||
|
renin | 0.370 | 0.923 | 2.4E-07 |
|
disease | 0.100 | None | 0.927 | 110 | 3 | 1986 | 2020 | ||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.100 | None | 0.907 | 108 | 5 | 1992 | 2020 | ||||||||
|
cytochrome P450 family 11 subfamily B member 2 | 0.553 | 0.615 | 7.1E-19 |
|
disease | 0.100 | None | 0.949 | 39 | 4 | 1995 | 2018 | ||||||||
|
hydroxysteroid 11-beta dehydrogenase 2 | 0.532 | 0.808 | 0.12 |
|
disease | 0.100 | None | 0.778 | 18 | 3 | 1996 | 2017 | ||||||||
|
adrenoceptor beta 2 | 0.442 | 0.923 | 0.53 |
|
disease | 0.100 | None | 1.000 | 14 | 5 | 1989 | 2017 | ||||||||
|
angiotensin I converting enzyme 2 | 0.477 | 0.769 | 1.00 |
|
disease | 0.100 | None | 0.929 | 14 | 9 | 2002 | 2019 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.100 | None | 0.909 | 11 | 3 | 2005 | 2018 | ||||||||
|
adrenoceptor beta 1 | 0.555 | 0.769 | 2.9E-06 |
|
disease | 0.100 | None | 0.900 | 10 | 2 | 2002 | 2018 | ||||||||
|
WNK lysine deficient protein kinase 4 | 0.644 | 0.538 | 6.9E-25 |
|
disease | 0.100 | None | 0.800 | 10 | 0 | 2003 | 2016 | ||||||||
|
solute carrier family 12 member 3 | 0.493 | 0.808 | 3.0E-32 |
|
disease | 0.100 | None | 0.900 | 10 | 6 | 2004 | 2015 | ||||||||
|
PGR antisense RNA 1 | 0.514 | 0.808 |
|
disease | 0.100 | None | 0.900 | 10 | 0 | 1998 | 2014 | |||||||||
|
endothelin 1 | 0.380 | 0.846 | 0.46 |
|
disease | 0.100 | None | 1.000 | 10 | 0 | 1995 | 2019 | ||||||||
|
solute carrier family 33 member 1 | 0.529 | 0.769 | 9.9E-05 |
|
disease | 0.090 | None | 0.889 | 9 | 0 | 1998 | 2014 | ||||||||
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
disease | 0.090 | None | 0.889 | 9 | 0 | 1998 | 2014 |