|
rs2228570
|
|
ovarian neoplasm
|
|
0.050 |
GeneticVariation
|
BEFREE |
The homozygote model with the rs2228570 (FokI) polymorphism model appeared to detect the risk of OC in all cases, whereas the heterozygote model with the rs1544410 (BsmI) polymorphism seemed to detect the risk of OC in Caucasian patients.
|
30059751 |
2018 |
|
rs2228570
|
|
ovarian neoplasm
|
|
0.050 |
GeneticVariation
|
BEFREE |
The rs2228570 polymorphism increased the risk of ovarian cancer in Caucasian populations in a dominant genetic model.
|
29239065 |
2018 |
|
rs2228570
|
|
Malignant neoplasm of ovary
|
|
0.050 |
GeneticVariation
|
BEFREE |
The rs2228570 polymorphism increased the risk of ovarian cancer in Caucasian populations in a dominant genetic model.
|
29239065 |
2018 |
|
rs2228570
|
|
Carcinoma, Ovarian Epithelial
|
|
0.050 |
GeneticVariation
|
BEFREE |
The rs2228570 polymorphism increased the risk of ovarian cancer in Caucasian populations in a dominant genetic model.
|
29239065 |
2018 |
|
rs2228570
|
|
Malignant neoplasm of ovary
|
|
0.050 |
GeneticVariation
|
BEFREE |
The VDR polymorphism FokI (rs2228570) seems to increase the risk of ovarian cancer.
|
29113037 |
2017 |
|
rs2228570
|
|
ovarian neoplasm
|
|
0.050 |
GeneticVariation
|
BEFREE |
The VDR polymorphism FokI (rs2228570) seems to increase the risk of ovarian cancer.
|
29113037 |
2017 |
|
rs2228570
|
|
Carcinoma, Ovarian Epithelial
|
|
0.050 |
GeneticVariation
|
BEFREE |
The VDR polymorphism FokI (rs2228570) seems to increase the risk of ovarian cancer.
|
29113037 |
2017 |
|
rs2228570
|
|
Asthma
|
|
0.050 |
GeneticVariation
|
BEFREE |
This meta-analysis provides convincing evidence that rs2228570, rs7975232, rs731236 and rs3782905 gene polymorphisms in VDR are associated with increased susceptibility to asthma, indicating VDR polymorphisms could be developed as biomarkers for asthma susceptibility.
|
27088875 |
2016 |
|
rs2228570
|
|
Malignant neoplasm of ovary
|
|
0.050 |
GeneticVariation
|
BEFREE |
More studies are warranted to assess the association between the VDR rs2228570 polymorphism and ovarian cancer in Asians and Africans.
|
24136742 |
2014 |
|
rs2228570
|
|
ovarian neoplasm
|
|
0.050 |
GeneticVariation
|
BEFREE |
More studies are warranted to assess the association between the VDR rs2228570 polymorphism and ovarian cancer in Asians and Africans.
|
24136742 |
2014 |
|
rs2228570
|
|
Carcinoma, Ovarian Epithelial
|
|
0.050 |
GeneticVariation
|
BEFREE |
More studies are warranted to assess the association between the VDR rs2228570 polymorphism and ovarian cancer in Asians and Africans.
|
24136742 |
2014 |
|
rs2228570
|
|
Carcinoma, Ovarian Epithelial
|
|
0.050 |
GeneticVariation
|
BEFREE |
This pooled analysis provides further evidence that the VDR rs2228570 polymorphism might influence ovarian cancer susceptibility.
|
20473893 |
2011 |
|
rs2228570
|
|
Asthma
|
|
0.050 |
GeneticVariation
|
BEFREE |
Within the asthma cohort, multiple significant associations between SNPs and asthma characteristics were identified; VDR SNP rs2228570 was associated with the higher nighttime asthma morbidity scores (P = 0.04), lower baseline spirometric measures (P < 0.05), 1 or more positive aeroallergen skin test (P = 0.003), and increased immunoglobulin E levels (P < 0.001).
|
21613960 |
2011 |
|
rs2228570
|
|
ovarian neoplasm
|
|
0.050 |
GeneticVariation
|
BEFREE |
This pooled analysis provides further evidence that the VDR rs2228570 polymorphism might influence ovarian cancer susceptibility.
|
20473893 |
2011 |
|
rs2228570
|
|
Malignant neoplasm of ovary
|
|
0.050 |
GeneticVariation
|
BEFREE |
This pooled analysis provides further evidence that the VDR rs2228570 polymorphism might influence ovarian cancer susceptibility.
|
20473893 |
2011 |
|
rs2228570
|
|
Multiple Sclerosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
These results suggest that VDR rs2228570 and rs731236 polymorphisms are not related with the risk for MS, and did not confirm interaction between these VDR SNPs and HLADRB1 in the risk for MS.
|
23840333 |
2013 |
|
rs2228570
|
|
Multiple Sclerosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
We found weak evidence for an association between the rs731236C allele and MS, while there was no direct association with rs2228570.
|
21816760 |
2012 |
|
rs2228570
|
|
Multiple Sclerosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
The aim of this study is to measure plasma levels of OPG and RANKL as well as to analyze VDR FokI polymorphism (rs2228570) in MS patients and healthy individuals to detect any potential correlation.
|
22805623 |
2012 |
|
rs2228570
|
|
Multiple Sclerosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
However, the VDR Fok1 variant (rs2228570), selected for previously positive associations with MS susceptibility and 25(OH)D levels in MS patients showed marginally distorted transmission in DRB15-negative patients (p=0.03).
|
21440908 |
2011 |
|
rs2228570
|
|
Parkinson Disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our meta-analysis suggested that VDR rs7975232 and rs2228570 variants might serve as genetic biomarkers of PD, whereas VDR rs731236 variant might serve as a genetic biomarker of AD.
|
30863943 |
2020 |
|
rs2228570
|
|
Parkinson Disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
Stratified study revealed that rs2228570 was associated with PD susceptibility in Asian population, while no significant association was observed in Caucasian population.
|
30763651 |
2019 |
|
rs2228570
|
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.030 |
GeneticVariation
|
BEFREE |
The association of FokI (rs2228570), a polymorphism of the vitamin D receptor gene, with intervertebral disc degeneration (IDD) has been investigated in a multitude of studies.
|
30309807 |
2019 |
|
rs2228570
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.030 |
GeneticVariation
|
BEFREE |
The G-allele and GG genotype of rs2228570 and T-allele and TT genotype of rs1544410 SNPs were associated with T2DM.
|
28323045 |
2018 |
|
rs2228570
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our study does not provide evidence for the association of the rs2228570 polymorphism with T2DM in a Caucasian population.
|
28388281 |
2017 |
|
rs2228570
|
|
Parkinson Disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
VDR SNP rs2228570 may be associated with sporadic PD in Japan.
|
28216333 |
2017 |