Gene: MSH6 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs587779267
rs587779267
MSH6 ; FBXO11
T 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312

2016
dbSNP: rs587782712
rs587782712
MSH6 ; FBXO11
T 0.700 CausalMutation CLINVAR Lynch syndrome mutation spectrum in New South Wales, Australia, including 55 novel mutations. 27064304

2016
dbSNP: rs63749942
rs63749942
MSH6 ; FBXO11
T 0.700 CausalMutation CLINVAR Germline multi-gene hereditary cancer panel testing in an unselected endometrial cancer cohort. 27443514

2016
dbSNP: rs63750111
rs63750111
MSH6 ; FBXO11
A 0.700 CausalMutation CLINVAR Mismatch repair gene mutation spectrum in the Swedish Lynch syndrome population. 27601186

2016
dbSNP: rs63750767
rs63750767
MSH6 ; FBXO11
TTCAAAAGGGACATAGAAAA 0.700 CausalMutation CLINVAR A cohort analysis of men with a family history of BRCA1/2 and Lynch mutations for prostate cancer. 27456091

2016
dbSNP: rs63750767
rs63750767
MSH6 ; FBXO11
TTCAAAAGGGACATAGAAAA 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312

2016
dbSNP: rs63750767
rs63750767
MSH6 ; FBXO11
TTCAAAAGGGACATAGAAAA 0.700 CausalMutation CLINVAR Improving performance of multigene panels for genomic analysis of cancer predisposition. 26845104

2016
dbSNP: rs730881816
rs730881816
MSH6 ; FBXO11
G 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312

2016
dbSNP: rs730881827
rs730881827
MSH6 ; FBXO11
T 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312

2016
dbSNP: rs730881830
rs730881830
MSH6 ; FBXO11
TTC 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312

2016
dbSNP: rs760190301
rs760190301
MSH6 ; FBXO11
AAGTT 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312

2016
dbSNP: rs863225421
rs863225421
MSH6 ; FBXO11
CG 0.700 CausalMutation CLINVAR Mismatch repair gene mutation spectrum in the Swedish Lynch syndrome population. 27601186

2016
dbSNP: rs864622153
rs864622153
MSH6 ; FBXO11
A 0.700 CausalMutation CLINVAR Mismatch repair gene mutation spectrum in the Swedish Lynch syndrome population. 27601186

2016
dbSNP: rs1060502886
rs1060502886
MSH6 ; FBXO11
C 0.700 CausalMutation CLINVAR Prognostic impact of mismatch repair genes germline defects in colorectal cancer patients: are all mutations equal? 26485756

2015
dbSNP: rs1060502888
rs1060502888
MSH6 ; FBXO11
A 0.700 CausalMutation CLINVAR Lynch-like syndrome: characterization and comparison with EPCAM deletion carriers. 25110875

2015
dbSNP: rs1060502926
rs1060502926
MSH6 ; FBXO11
A 0.700 CausalMutation CLINVAR Multigene panel analysis identified germline mutations of DNA repair genes in breast and ovarian cancer. 26436112

2015
dbSNP: rs146816935
rs146816935
MSH6 ; FBXO11
T 0.700 CausalMutation CLINVAR Combined Microsatellite Instability, MLH1 Methylation Analysis, and Immunohistochemistry for Lynch Syndrome Screening in Endometrial Cancers From GOG210: An NRG Oncology and Gynecologic Oncology Group Study. 26552419

2015
dbSNP: rs1553333175
rs1553333175
MSH6 ; FBXO11
A 0.700 GeneticVariation CLINVAR [Constitutional mismatch repair deficiency syndrome]. 26200421

2015
dbSNP: rs1553408388
rs1553408388
MSH6
T 0.700 CausalMutation CLINVAR Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome. 25980754

2015
dbSNP: rs267608042
rs267608042
MSH6 ; FBXO11
C 0.700 CausalMutation CLINVAR Clinical characterization and mutation spectrum in Caribbean Hispanic families with Lynch syndrome. 25782445

2015
dbSNP: rs267608077
rs267608077
MSH6 ; FBXO11
A 0.700 CausalMutation CLINVAR Impact of an immunohistochemistry-based universal screening protocol for Lynch syndrome in endometrial cancer on genetic counseling and testing. 25617771

2015
dbSNP: rs267608078
rs267608078
MSH6 ; FBXO11
AC 0.700 CausalMutation CLINVAR Constitutional mismatch repair deficiency syndrome: clinical description in a French cohort. 26318770

2015
dbSNP: rs267608094
rs267608094
MSH6 ; FBXO11
T 0.700 CausalMutation CLINVAR Constitutional mismatch repair deficiency syndrome: clinical description in a French cohort. 26318770

2015
dbSNP: rs267608098
rs267608098
MSH6 ; FBXO11
G 0.700 CausalMutation CLINVAR Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome. 25980754

2015
dbSNP: rs267608120
rs267608120
MSH6 ; FBXO11
A 0.700 CausalMutation CLINVAR Genetic features of Lynch syndrome in the Israeli population. 25430799

2015