Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 239 0
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 151 0
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885 97 0
GCG P01275 glucagon 3.5E-02 0.431 0.885 43 0
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846 42 0
FASN P49327 fatty acid synthase Enzyme 1.00 0.474 0.846 42 0
PEBP1 P30086 phosphatidylethanolamine binding protein 1 Enzyme modulator 9.2E-02 0.500 0.808 23 0
GDF15 Q99988 growth differentiation factor 15 Signaling 3.0E-07 0.429 0.808 21 0
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885 18 0
PDPK1 O15530 3-phosphoinositide dependent protein kinase 1 Kinase 0.98 0.588 0.808 14 0
ADRA2C P18825 adrenoceptor alpha 2C G-protein coupled receptor 0.50 0.682 0.346 12 0
APCS P02743 amyloid P component, serum 3.2E-02 0.531 0.808 12 0
PPP1R1A Q13522 protein phosphatase 1 regulatory inhibitor subunit 1A Enzyme modulator 2.2E-02 0.559 0.692 11 0
CIDEA O60543 cell death inducing DFFA like effector a 5.6E-06 0.751 0.269 10 0
BAMBI Q13145 BMP and activin membrane bound inhibitor 2.1E-04 0.619 0.692 10 0
DSTN P60981 destrin, actin depolymerizing factor 0.55 0.644 0.692 9 0
UCP1 P25874 uncoupling protein 1 Transporter 1.7E-11 0.545 0.769 9 0
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 285 1
IFNG P01579 interferon gamma 0.47 0.288 0.962 167 1
PLAT P00750 plasminogen activator, tissue type Enzyme 5.7E-05 0.445 0.885 136 1
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 109 1
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 89 1
ADRB1 P08588 adrenoceptor beta 1 G-protein coupled receptor 2.9E-06 0.555 0.769 27 1
SOX4 Q06945 SRY-box transcription factor 4 Transcription factor 0.93 0.489 0.808 24 1