Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 270 4
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 241 7
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 231 5
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 184 9
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 168 2
IFNG P01579 interferon gamma 0.47 0.288 0.962 167 1
INS P01308 insulin 0.30 0.445 0.923 157 34
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 138 5
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 137 3
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885 112 15
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 80 6
GHRL Q9UBU3 ghrelin and obestatin prepropeptide 1.4E-11 0.517 0.769 68 4
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 66 6
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769 64 6
NPPB P16860 natriuretic peptide B 9.9E-06 0.513 0.808 48 2
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808 47 26
GCG P01275 glucagon 3.5E-02 0.431 0.885 43 0
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923 41 27
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923 34 2
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846 26 3
GATM P50440 glycine amidinotransferase 5.1E-02 0.666 0.615 18 23
HAND2 P61296 heart and neural crest derivatives expressed 2 0.40 0.612 0.500 18 2
OLR1 P78380 oxidized low density lipoprotein receptor 1 7.2E-03 0.544 0.769 16 2
RETN Q9HD89 resistin 3.7E-02 0.454 0.808 16 2