Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 340 9
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 285 1
IL6 P05231 interleukin 6 0.32 0.248 0.962 270 4
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846 241 7
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 239 0
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 231 5
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 184 9
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 171 2
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 168 2
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 167 4
IFNG P01579 interferon gamma 0.47 0.288 0.962 167 1
INS P01308 insulin 0.30 0.445 0.923 157 34
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 151 0
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962 147 48
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 146 14
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 138 5
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 137 3
PLAT P00750 plasminogen activator, tissue type Enzyme 5.7E-05 0.445 0.885 136 1
ALB P02768 albumin Transporter 0.64 0.317 0.962 123 9
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 113 9
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885 112 15
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 110 65
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 109 1
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 103 3