Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 92
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 99
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 234
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 111
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 128
MIR21 microRNA 21 0.363 0.846 28
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 40
SST P61278 somatostatin Signaling 0.34 0.399 0.885 51
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 67
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885 95
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885 47
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885 102
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 28
IL15 P40933 interleukin 15 0.71 0.422 0.846 6
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885 51
TGFB2 P61812 transforming growth factor beta 2 Signaling 1.00 0.433 0.885 24
TNC P24821 tenascin C 1.3E-07 0.433 0.846 10
DKK1 O94907 dickkopf WNT signaling pathway inhibitor 1 0.17 0.439 0.885 7
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808 109
DICER1 Q9UPY3 dicer 1, ribonuclease III Enzyme 1.00 0.446 0.846 10
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923 28
IDO1 P14902 indoleamine 2,3-dioxygenase 1 3.3E-06 0.454 0.846 14
HDAC1 Q13547 histone deacetylase 1 Epigenetic regulator 0.61 0.460 0.846 12
CXCL9 Q07325 C-X-C motif chemokine ligand 9 Signaling 2.9E-03 0.462 0.808 35