Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
MIR21 microRNA 21 0.363 0.846 28
SRD5A2 P31213 steroid 5 alpha-reductase 2 Enzyme 0.564 0.615 18
CDKN2B-AS1 CDKN2B antisense RNA 1 0.491 0.769 11
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808 20
AKR1C3 P42330 aldo-keto reductase family 1 member C3 Enzyme 7.6E-24 0.529 0.769 23
LAMB1 P07942 laminin subunit beta 1 Enzyme modulator 5.1E-22 0.615 0.654 11
LTF P02788 lactotransferrin Enzyme 1.3E-21 0.543 0.846 37
SMPDL3A Q92484 sphingomyelin phosphodiesterase acid like 3A Enzyme 6.3E-21 0.890 0.115 2
AKR1C1 Q04828 aldo-keto reductase family 1 member C1 Enzyme 3.5E-15 0.593 0.615 18
MED16 Q9Y2X0 mediator complex subunit 16 2.6E-14 0.890 0.192 2
SUCLG2 Q96I99 succinate-CoA ligase GDP-forming subunit beta Enzyme 5.7E-14 0.780 0.308 6
RXFP1 Q9HBX9 relaxin family peptide receptor 1 G-protein coupled receptor 1.4E-12 0.659 0.538 2
CD55 P08174 CD55 molecule (Cromer blood group) 5.7E-12 0.510 0.808 7
ITGA2 P17301 integrin subunit alpha 2 6.3E-11 0.522 0.731 14
AKR1C2 P52895 aldo-keto reductase family 1 member C2 Enzyme 6.9E-11 0.608 0.577 19
HERC5 Q9UII4 HECT and RLD domain containing E3 ubiquitin protein ligase 5 7.7E-11 0.674 0.462 4
CYP26A1 O43174 cytochrome P450 family 26 subfamily A member 1 Enzyme 8.4E-11 0.619 0.577 18
HSD17B2 P37059 hydroxysteroid 17-beta dehydrogenase 2 Enzyme 1.8E-10 0.656 0.385 5
ANKRD1 Q15327 ankyrin repeat domain 1 2.6E-10 0.628 0.692 2
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923 28
SPARCL1 Q14515 SPARC like 1 Signaling 5.6E-10 0.604 0.615 6
ARHGAP28 Q9P2N2 Rho GTPase activating protein 28 Enzyme modulator 2.6E-09 0.890 0.077 2
MED17 Q9NVC6 mediator complex subunit 17 3.1E-09 0.769 0.269 3
GREB1 Q4ZG55 growth regulating estrogen receptor binding 1 6.6E-09 0.663 0.385 4