Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 69
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 44
BAD Q92934 BCL2 associated agonist of cell death 4.6E-03 0.553 0.769 30
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 18
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923 16
SHH Q15465 sonic hedgehog signaling molecule 0.98 0.461 0.846 13
GFRA1 P56159 GDNF family receptor alpha 1 0.12 0.619 0.615 5
NDUFS3 O75489 NADH:ubiquinone oxidoreductase core subunit S3 5.8E-04 0.581 0.769 4
HSPA9 P38646 heat shock protein family A (Hsp70) member 9 0.97 0.502 0.885 2
GFRA2 O00451 GDNF family receptor alpha 2 9.8E-02 0.716 0.423 1
PDE1B Q01064 phosphodiesterase 1B 0.34 0.769 0.423 1
RGS9 O75916 regulator of G protein signaling 9 1.1E-14 0.722 0.308 1
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 27
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 76
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 62
CASP9 P55211 caspase 9 Enzyme 7.4E-06 0.458 0.808 37
GSR P00390 glutathione-disulfide reductase Enzyme 1.3E-06 0.494 0.846 31
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885 24
ABAT P80404 4-aminobutyrate aminotransferase Enzyme 6.3E-03 0.628 0.538 16
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 7
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846 7
ENO2 P09104 enolase 2 Enzyme 0.38 0.475 0.846 6
COX1 P00395 cytochrome c oxidase subunit I Enzyme 0.441 0.885 6