Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
FKBP1A P62942 FKBP prolyl isomerase 1A Enzyme 0.81 0.641 0.654 1
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846 39
CX3CR1 P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 6.1E-02 0.457 0.885 26
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846 23
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808 19
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692 7
GRM8 O00222 glutamate metabotropic receptor 8 G-protein coupled receptor 4.5E-07 0.636 0.577 3
KCNJ11 Q14654 potassium inwardly rectifying channel subfamily J member 11 Ion channel 1.1E-02 0.529 0.615 9
KCNJ8 Q15842 potassium inwardly rectifying channel subfamily J member 8 Ion channel 0.38 0.619 0.538 6
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 15
SRC P12931 SRC proto-oncogene, non-receptor tyrosine kinase Kinase 1.00 0.467 0.885 7
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885 4
LYN P07948 LYN proto-oncogene, Src family tyrosine kinase Kinase 1.00 0.603 0.615 3
GSK3A P49840 glycogen synthase kinase 3 alpha Kinase 1.00 0.644 0.538 2
PINK1 Q9BXM7 PTEN induced kinase 1 Kinase 1.9E-10 0.516 0.769 2
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962 21
CX3CL1 P78423 C-X3-C motif chemokine ligand 1 Signaling 0.61 0.478 0.808 27
VIP P01282 vasoactive intestinal peptide Signaling 4.2E-04 0.437 0.846 9
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 8
UCN P55089 urocortin Signaling 0.45 0.539 0.769 6
ADCYAP1 P18509 adenylate cyclase activating polypeptide 1 Signaling 0.52 0.510 0.846 5
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885 2
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885 26
NFKB2 Q00653 nuclear factor kappa B subunit 2 Transcription factor 1.00 0.509 0.808 3