Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846 8
ADAM17 P78536 ADAM metallopeptidase domain 17 1.00 0.453 0.808 9
ADAM9 Q13443 ADAM metallopeptidase domain 9 Enzyme 2.9E-02 0.560 0.654 3
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 43
APLP2 Q06481 amyloid beta precursor like protein 2 Enzyme modulator 0.38 0.659 0.462 3
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846 7
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 34
ATP5F1A P25705 ATP synthase F1 subunit alpha Transporter 1.00 0.604 0.731 11
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769 13
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 62
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 44
BCL2L2 Q92843 BCL2 like 2 Signaling 0.47 0.599 0.615 4
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769 10
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 35
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885 26
CIB1 Q99828 calcium and integrin binding 1 3.3E-04 0.458 0.769 1
CASP12 Q6UXS9 caspase 12 (gene/pseudogene) 1.3E-04 0.638 0.808 23
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 62
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 35
CASP9 P55211 caspase 9 Enzyme 7.4E-06 0.458 0.808 37
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 17
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885 22
CHAT P28329 choline O-acetyltransferase Enzyme 5.6E-11 0.520 0.808 3