Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
NGB Q9NPG2 neuroglobin Transporter 4.5E-03 0.631 0.462 6
APLP2 Q06481 amyloid beta precursor like protein 2 Enzyme modulator 0.38 0.659 0.462 3
INS-IGF2 F8WCM5 INS-IGF2 readthrough 5.6E-02 0.633 0.500 2
IDE P14735 insulin degrading enzyme Enzyme 6.6E-03 0.604 0.577 6
BCL2L2 Q92843 BCL2 like 2 Signaling 0.47 0.599 0.615 4
PLCB1 Q9NQ66 phospholipase C beta 1 Enzyme 0.98 0.595 0.654 3
ADAM9 Q13443 ADAM metallopeptidase domain 9 Enzyme 2.9E-02 0.560 0.654 3
MAP2 P11137 microtubule associated protein 2 1.00 0.537 0.692 9
DNM1 Q05193 dynamin 1 Enzyme modulator 1.00 0.595 0.692 2
ATP5F1A P25705 ATP synthase F1 subunit alpha Transporter 1.00 0.604 0.731 11
IRS1 P35568 insulin receptor substrate 1 2.4E-02 0.488 0.769 13
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769 13
HSF1 Q00613 heat shock transcription factor 1 Transcription factor 0.75 0.507 0.769 12
LRP1 Q07954 LDL receptor related protein 1 1.00 0.482 0.769 12
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769 10
PIN1 Q13526 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.74 0.488 0.769 5
CIB1 Q99828 calcium and integrin binding 1 3.3E-04 0.458 0.769 1
CASP9 P55211 caspase 9 Enzyme 7.4E-06 0.458 0.808 37
CASP12 Q6UXS9 caspase 12 (gene/pseudogene) 1.3E-04 0.638 0.808 23
HSPD1 P10809 heat shock protein family D (Hsp60) member 1 0.99 0.432 0.808 20
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808 14
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808 12
GAPDH P04406 glyceraldehyde-3-phosphate dehydrogenase Enzyme 0.11 0.447 0.808 10
MT2A P02795 metallothionein 2A 1.2E-05 0.553 0.808 9