Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923 64
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808 12
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 43
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 60
CHAT P28329 choline O-acetyltransferase Enzyme 5.6E-11 0.520 0.808 3
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885 26
IL33 O95760 interleukin 33 8.3E-10 0.409 0.885 1
SERPINF1 P36955 serpin family F member 1 Enzyme modulator 7.8E-08 0.460 0.846 20
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808 6
PTGS1 P23219 prostaglandin-endoperoxide synthase 1 Enzyme 6.2E-07 0.460 0.885 19
GSR P00390 glutathione-disulfide reductase Enzyme 1.3E-06 0.494 0.846 31
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923 34
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 35
CASP9 P55211 caspase 9 Enzyme 7.4E-06 0.458 0.808 37
MT2A P02795 metallothionein 2A 1.2E-05 0.553 0.808 9
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846 21
CASP12 Q6UXS9 caspase 12 (gene/pseudogene) 1.3E-04 0.638 0.808 23
CIB1 Q99828 calcium and integrin binding 1 3.3E-04 0.458 0.769 1
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 34
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 23
NGB Q9NPG2 neuroglobin Transporter 4.5E-03 0.631 0.462 6
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923 16
IDE P14735 insulin degrading enzyme Enzyme 6.6E-03 0.604 0.577 6
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885 22