Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 32
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808 38
MSLN Q13421 mesothelin Extracellular structure 5.9E-25 0.525 0.692 10
TGM2 P21980 transglutaminase 2 Enzyme 6.8E-18 0.445 0.808 19
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 149
GJB2 P29033 gap junction protein beta 2 Cell-cell junction 6.6E-16 0.441 0.846 22
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808 13
RAD54L Q92698 RAD54 like 2.4E-15 0.633 0.423 1
MTRR Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 2.2E-14 0.502 0.808 19
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808 18
CTSB P07858 cathepsin B Enzyme 5.9E-11 0.457 0.846 17
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 110
CA9 Q16790 carbonic anhydrase 9 1.3E-09 0.483 0.731 19
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885 28
TNC P24821 tenascin C 1.3E-07 0.433 0.846 26
ITGA3 P26006 integrin subunit alpha 3 3.6E-07 0.573 0.731 12
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923 46
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 33
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808 28
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 171
MMP11 P24347 matrix metallopeptidase 11 Enzyme 2.4E-05 0.542 0.692 5
CBS P0DN79 P35520 cystathionine beta-synthase Enzyme 3.1E-05 0.465 0.885 13
EPB41 P11171 erythrocyte membrane protein band 4.1 3.6E-05 0.691 0.500 3
EPB41L3 Q9Y2J2 erythrocyte membrane protein band 4.1 like 3 4.3E-05 0.619 0.615 7