Source: LHGDN

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 59
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923 55
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 55
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 53
MBL2 P11226 mannose binding lectin 2 Receptor 2.7E-03 0.390 0.846 53
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885 52
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885 52
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808 50
SELE P16581 selectin E 7.9E-10 0.447 0.808 49
ADM P35318 adrenomedullin Signaling 4.1E-02 0.436 0.808 43
GHRL Q9UBU3 ghrelin and obestatin prepropeptide 1.4E-11 0.517 0.769 43
NPPB P16860 natriuretic peptide B 9.9E-06 0.513 0.808 42
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 41
F3 P13726 coagulation factor III, tissue factor Receptor 1.9E-02 0.415 0.846 41
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808 41
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846 40
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 37
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923 33
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808 33
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846 32
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885 31
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846 29
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885 29
ENG P17813 endoglin 1.00 0.446 0.846 28