Source: CGI

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
BLM P54132 BLM RecQ like helicase 1.5E-15 0.535 0.808 4
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808 20
RAD54L Q92698 RAD54 like 2.4E-15 0.633 0.423 2
TSHR P16473 thyroid stimulating hormone receptor G-protein coupled receptor 3.0E-15 0.486 0.808 1
PDGFRL Q15198 platelet derived growth factor receptor like Enzyme 1.2E-14 0.769 0.385 1
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808 2
FANCG O15287 FA complementation group G 2.5E-14 0.556 0.769 2
ERCC5 P28715 ERCC excision repair 5, endonuclease 2.7E-13 0.499 0.731 4
FANCC Q00597 FA complementation group C 2.8E-13 0.507 0.808 8
FGFR4 P22455 fibroblast growth factor receptor 4 Kinase 7.2E-13 0.490 0.769 1
RAD54B O95073 Q9Y620 RAD54 homolog B 8.1E-13 0.659 0.462 2
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846 8
TRAF5 O00463 TNF receptor associated factor 5 Signaling 1.7E-12 0.659 0.654 1
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808 9
RBBP8 Q99708 RB binding protein 8, endonuclease Transcription factor 3.1E-12 0.584 0.808 4
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808 1
CASP10 Q92851 caspase 10 Enzyme 4.6E-12 0.528 0.692 7
PTPRJ Q12913 protein tyrosine phosphatase receptor type J Enzyme 1.3E-11 0.606 0.615 1
ERCC3 P19447 ERCC excision repair 3, TFIIH core complex helicase subunit Enzyme 3.4E-11 0.504 0.846 4
XPC Q01831 XPC complex subunit, DNA damage recognition and repair factor Nucleic acid binding 3.7E-11 0.504 0.808 4
CBLC Q9ULV8 Cbl proto-oncogene C Enzyme 4.2E-11 0.821 0.192 1
CSF3R Q99062 colony stimulating factor 3 receptor Signaling 1.5E-10 0.550 0.692 7
BUB1B O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 7.0E-10 0.502 0.808 1
EXT2 Q93063 exostosin glycosyltransferase 2 Enzyme 1.3E-09 0.576 0.654 1