Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 23
AGTR2 P50052 angiotensin II receptor type 2 G-protein coupled receptor 8.2E-03 0.496 0.808 22
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885 21
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846 21
VCAM1 P19320 vascular cell adhesion molecule 1 0.80 0.422 0.808 21
ABCC3 O15438 ATP binding cassette subfamily C member 3 Transporter 1.2E-26 0.517 0.769 20
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654 19
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692 18
EPOR P19235 erythropoietin receptor Receptor 1.0E-02 0.526 0.692 17
KL Q9UEF7 klotho Enzyme 2.2E-04 0.448 0.769 17
LPL P06858 lipoprotein lipase Enzyme 1.3E-09 0.474 0.808 17
ABCC2 Q92887 ATP binding cassette subfamily C member 2 Transporter 5.2E-47 0.483 0.808 16
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808 16
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846 15
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846 15
SHH Q15465 sonic hedgehog signaling molecule 0.98 0.461 0.846 15
BNIP3 Q12983 BCL2 interacting protein 3 2.0E-05 0.520 0.731 14
CLU P10909 clusterin 7.8E-05 0.426 0.885 14
CYBB P04839 cytochrome b-245 beta chain Ion channel 1.00 0.452 0.885 14
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846 14
POSTN Q15063 periostin Signaling 1.1E-09 0.428 0.885 14
PTGER4 P35408 prostaglandin E receptor 4 G-protein coupled receptor 0.98 0.558 0.731 14
BGLAP P02818 bone gamma-carboxyglutamate protein 4.6E-08 0.462 0.846 13
IRS1 P35568 insulin receptor substrate 1 2.4E-02 0.488 0.769 13