Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CYBB P04839 cytochrome b-245 beta chain Ion channel 1.00 0.452 0.885 14
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846 14
DGAT1 O75907 diacylglycerol O-acyltransferase 1 Enzyme 1.4E-17 0.621 0.615 3
DGAT2 Q96PD7 diacylglycerol O-acyltransferase 2 Enzyme 8.4E-12 0.686 0.423 7
DDC P20711 dopa decarboxylase 3.8E-08 0.535 0.769 9
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808 16
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808 5
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846 48
EPOR P19235 erythropoietin receptor Receptor 1.0E-02 0.526 0.692 17
FGF23 Q9GZV9 fibroblast growth factor 23 Signaling 3.1E-02 0.460 0.731 5
FIS1 Q9Y3D6 fission, mitochondrial 1 1.3E-05 0.663 0.769 12
GTPBP4 Q9BZE4 GTP binding protein 4 1.00 0.769 0.346 2
HP P00738 haptoglobin Enzyme 1.7E-05 0.412 0.885 30
HAVCR1 Q96D42 hepatitis A virus cellular receptor 1 8.5E-07 0.489 0.885 10
HAMP P81172 hepcidin antimicrobial peptide 8.2E-03 0.433 0.846 24
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846 21
IRS1 P35568 insulin receptor substrate 1 2.4E-02 0.488 0.769 13
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962 55
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
IL20 Q9NYY1 interleukin 20 1.3E-06 0.556 0.769 2
KEAP1 Q14145 kelch like ECH associated protein 1 3.9E-04 0.475 0.808 6
KL Q9UEF7 klotho Enzyme 2.2E-04 0.448 0.769 17
LRP2 P98164 LDL receptor related protein 2 1.00 0.491 0.846 12
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654 6