Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
LPL P06858 lipoprotein lipase Enzyme 1.3E-09 0.474 0.808 17
LRP2 P98164 LDL receptor related protein 2 1.00 0.491 0.846 12
MFN1 Q8IWA4 mitofusin 1 Enzyme 2.5E-10 0.644 0.577 10
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 44
NAT2 P11245 N-acetyltransferase 2 Enzyme 3.3E-06 0.451 0.885 2
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 23
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 46
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 72
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885 40
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 28
NR4A1 P22736 nuclear receptor subfamily 4 group A member 1 Nuclear receptor 0.37 0.490 0.731 2
OLR1 P78380 oxidized low density lipoprotein receptor 1 7.2E-03 0.544 0.769 4
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846 15
PCSK2 P16519 proprotein convertase subtilisin/kexin type 2 Enzyme 1.00 0.663 0.462 5
PGF P49763 placental growth factor Signaling 0.13 0.460 0.846 11
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923 34
POSTN Q15063 periostin Signaling 1.1E-09 0.428 0.885 14
PTGER4 P35408 prostaglandin E receptor 4 G-protein coupled receptor 0.98 0.558 0.731 14
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846 15
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885 26
RNLS Q5VYX0 renalase, FAD dependent amine oxidase 3.8E-06 0.678 0.423 6
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885 48
SHH Q15465 sonic hedgehog signaling molecule 0.98 0.461 0.846 15
SLC19A1 P41440 solute carrier family 19 member 1 Transporter 6.5E-06 0.523 0.692 1