Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0009197
Disease: Cochlear Diseases
Cochlear Diseases 		0.200 Therapeutic RGD The expression of oxidative stress response genes is modulated by a combination of resveratrol and N-acetylcysteine to ameliorate ototoxicity in the rat cochlea. 29304389

2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0014534
Disease: Epididymitis
Epididymitis 		0.200 Biomarker RGD Lipopolysaccharide and lipotheicoic acid differentially modulate epididymal cytokine and chemokine profiles and sperm parameters in experimental acute epididymitis. 29311626

2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0021655
Disease: Insulin Resistance
Insulin Resistance 		0.200 Therapeutic RGD N-Acetyl-l-Cysteine treatment efficiently prevented pre-diabetes and inflamed-dysmetabolic liver development in hypothalamic obese rats. 29522769

2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0152025
Disease: Polyneuropathy
Polyneuropathy 		0.200 Therapeutic RGD Involvement of α7nAChR in electroacupuncture relieving neuropathic pain in the spinal cord of rat with spared nerve injury. 29307658

2018
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0375359
Disease: Chronic left-sided ulcerative colitis
Chronic left-sided ulcerative colitis 		0.200 Biomarker RGD "[Exploration of the theory of ""Fei and Dachang being interior-exteriorly related"" from observing changes of inflammatory cytokines and oxygen free radicals in the lung tissue of ulcerative colitis rats]." 24812904

2014
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0343387
Disease: Enterocolitis, Neutropenic
Enterocolitis, Neutropenic 		0.200 Biomarker RGD CDP-choline reduces severity of intestinal injury in a neonatal rat model of necrotizing enterocolitis. 23228325

2013
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0520459
Disease: Necrotizing Enterocolitis
Necrotizing Enterocolitis 		0.200 Biomarker RGD Intestinal alkaline phosphatase prevents the systemic inflammatory response associated with necrotizing enterocolitis. 23158403

2013
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0027720
Disease: Nephrosis
Nephrosis 		0.200 Biomarker RGD Protective effects of sinomenine against doxorubicin-induced nephrosis in rats. 22582804

2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0029799
Disease: Other specified forms of pleural effusion, except tuberculous
Other specified forms of pleural effusion, except tuberculous 		0.200 Biomarker RGD Anti-inflammation effects of corn silk in a rat model of carrageenin-induced pleurisy. 21898269

2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0149940
Disease: Sciatic Neuropathy
Sciatic Neuropathy 		0.200 Therapeutic RGD Effects of intrathecal epigallocatechin gallate, an inhibitor of Toll-like receptor 4, on chronic neuropathic pain in rats. 22173123

2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0157946
Disease: Osteoarthrosis, localized, not specified whether primary or secondary
Osteoarthrosis, localized, not specified whether primary or secondary 		0.200 Therapeutic RGD Rebamipide attenuates pain severity and cartilage degeneration in a rat model of osteoarthritis by downregulating oxidative damage and catabolic activity in chondrocytes. 22890185

2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0752235
Disease: Lyme Neuroborreliosis
Lyme Neuroborreliosis 		0.200 Biomarker RGD Acetate supplementation reduces microglia activation and brain interleukin-1β levels in a rat model of Lyme neuroborreliosis. 23134838

2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C1541844
Disease: PRESENILE AND SENILE DEMENTIA
PRESENILE AND SENILE DEMENTIA 		0.200 Biomarker RGD [Regulating effect of Ginkgo biloba extract 50 on hippocampal inflammation-related cytokines in senile rats]. 23126199

2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD Inhibition of poly(ADP-ribose) polymerase attenuates acute kidney injury in sodium taurocholate-induced acute pancreatitis in rats. 22750969

2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.200 Biomarker RGD Erythropoietin attenuates cardiopulmonary bypass-induced renal inflammatory injury by inhibiting nuclear factor-κB p65 expression. 22659586

2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0017662
Disease: Glomerulonephritis, Membranoproliferative
Glomerulonephritis, Membranoproliferative 		0.200 Biomarker RGD Eicosapentaenoic acid regulates IκBα and prevents tubulointerstitial injury in kidney. 21871881

2011
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0026766
Disease: Multiple Organ Failure
Multiple Organ Failure 		0.200 Biomarker RGD Therapeutic effects of melatonin on heatstroke-induced multiple organ dysfunction syndrome in rats. 21392091

2011
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0029866
Disease: Other ureteric obstruction
Other ureteric obstruction 		0.200 Biomarker RGD The effects of dietary fish oil on inflammation, fibrosis and oxidative stress associated with obstructive renal injury in rats. 21370451

2011
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion 		0.200 Biomarker RGD Effects of intravitreal triamcinolone acetonide on retinal gene expression in a rat model of central retinal vein occlusion. 21487926

2011
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0035455
Disease: Rhinitis
Rhinitis 		0.200 Biomarker RGD Nuclear factor kappa B pathway down-regulates aquaporin 5 in the nasal mucosa of rats with allergic rhinitis. 20490816

2011
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0036982
Disease: Shock, Hemorrhagic
Shock, Hemorrhagic 		0.200 ModifyingMutation RGD A quantitative study of p38 mitogen-activated protein kinase on renal dysfunction after hemorrhagic shock in rats. 21336199

2011
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0017665
Disease: Membranous glomerulonephritis
Membranous glomerulonephritis 		0.200 Biomarker RGD Corticosteroids worsen proteinuria and increase intraglomerular signaling by NF-ĸB in a model of membranous glomerulonephritis. 20588061

2010
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0178664
Disease: Glomerulosclerosis (disorder)
Glomerulosclerosis (disorder) 		0.200 Biomarker RGD Renoprotective effect of rosuvastatin in DOCA-salt hypertensive rats. 19948880

2010
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0027814
Disease: Neuritis, Autoimmune, Experimental
Neuritis, Autoimmune, Experimental 		0.200 Therapeutic RGD Improved outcome of EAN, an animal model of GBS, through amelioration of peripheral and central inflammation by minocycline. 18400050

2009
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0029799
Disease: Other specified forms of pleural effusion, except tuberculous
Other specified forms of pleural effusion, except tuberculous 		0.200 Biomarker RGD Anti-inflammatory effects of low molecular weight heparin derivative in a rat model of carrageenan-induced pleurisy. 20141620

2009