Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7450
Gene Symbol: VWF
VWF
von Willebrand factor 0.408 0.885 3.2E-25
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.200 None 1.000 10 0 2016 2020
Entrez Id: 171389
Gene Symbol: NLRP6
NLRP6
NLR family pyrin domain containing 6 0.628 0.769 2.7E-04
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.080 None 1.000 8 0 2017 2019
Entrez Id: 5972
Gene Symbol: REN
REN
renin 0.370 0.923 2.4E-07
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.080 None 1.000 8 0 2001 2019
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
galectin 3 0.392 0.846 2.3E-05
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.050 None 1.000 5 0 2016 2018
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.040 None 1.000 4 0 1997 2017
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.050 None 1.000 4 0 1996 2020
Entrez Id: 348
Gene Symbol: APOE
APOE
apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.050 None 0.600 4 0 2001 2017
Entrez Id: 54873
Gene Symbol: PALMD
PALMD
palmdelphin 0.931 0.115 3.4E-04
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.030 None 1.000 3 0 2018 2019
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B
TNF receptor superfamily member 11b 0.422 0.808 0.16
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.040 None 1.000 3 0 2004 2018
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.030 None 1.000 3 0 2004 2019
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.353 0.885 2.1E-06
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.030 None 1.000 3 0 1995 2017
Entrez Id: 4142
Gene Symbol: MAS1
MAS1
MAS1 proto-oncogene, G protein-coupled receptor 0.533 0.769 8.3E-05
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.030 None 0.667 3 0 2011 2019
Entrez Id: 2335
Gene Symbol: FN1
FN1
fibronectin 1 0.365 0.962 1.4E-03
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.030 None 1.000 3 0 2001 2011
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
sirtuin 1 0.378 0.885 8.7E-02
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.020 None 1.000 2 0 2012 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.220 None 1.000 2 0 2005 2018
Entrez Id: 56729
Gene Symbol: RETN
RETN
resistin 0.454 0.808 3.7E-02
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.020 None 1.000 2 0 2012 2019
Entrez Id: 335
Gene Symbol: APOA1
APOA1
apolipoprotein A1 0.429 0.885 5.5E-04
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.020 None 1.000 2 0 2018 2018
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.318 0.885 0.27
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.020 None 1.000 2 0 1997 2017
Entrez Id: 59272
Gene Symbol: ACE2
ACE2
angiotensin I converting enzyme 2 0.477 0.769 1.00
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.020 None 1.000 2 0 2011 2020
Entrez Id: 197
Gene Symbol: AHSG
AHSG
alpha 2-HS glycoprotein 0.506 0.846 3.2E-10
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.020 None 0.500 2 0 2017 2018
Entrez Id: 4880
Gene Symbol: NPPC
NPPC
natriuretic peptide C 0.568 0.769 6.1E-02
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.220 None 1.000 2 0 2007 2019
Entrez Id: 6385
Gene Symbol: SDC4
SDC4
syndecan 4 0.603 0.615 4.1E-03
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.020 None 1.000 2 0 2011 2019
Entrez Id: 5444
Gene Symbol: PON1
PON1
paraoxonase 1 0.409 0.885 9.8E-11
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.020 None 1.000 2 0 2018 2019
Entrez Id: 2214
Gene Symbol: FCGR3A
FCGR3A
Fc fragment of IgG receptor IIIa 0.432 0.962 3.7E-06
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.020 None 1.000 2 0 2017 2017
Entrez Id: 22915
Gene Symbol: MMRN1
MMRN1
multimerin 1 0.465 0.846 2.1E-25
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.020 None 1.000 2 0 2011 2017