Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.220 None 1.000 2 0 2005 2018
Entrez Id: 4880
Gene Symbol: NPPC
NPPC
natriuretic peptide C 0.568 0.769 6.1E-02
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.220 None 1.000 2 0 2007 2019
Entrez Id: 7450
Gene Symbol: VWF
VWF
von Willebrand factor 0.408 0.885 3.2E-25
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.200 None 1.000 10 0 2016 2020
Entrez Id: 140628
Gene Symbol: GATA5
GATA5
GATA binding protein 5 0.578 0.615 0.28
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.110 None 1.000 1 0 2011 2011
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
notch receptor 1 0.369 0.885 1.00
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.110 None 1.000 1 0 2017 2017
Entrez Id: 10682
Gene Symbol: EBP
EBP
EBP cholestenol delta-isomerase 0.494 0.846 0.94
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.110 None 1.000 1 0 2017 2017
Entrez Id: 2626
Gene Symbol: GATA4
GATA4
GATA binding protein 4 0.458 0.846 0.49
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.110 None 1.000 1 0 2011 2011
Entrez Id: 4018
Gene Symbol: LPA
LPA
lipoprotein(a) 0.444 0.769 6.6E-89
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.100 None 0.909 33 2 2014 2019
Entrez Id: 171389
Gene Symbol: NLRP6
NLRP6
NLR family pyrin domain containing 6 0.628 0.769 2.7E-04
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.080 None 1.000 8 0 2017 2019
Entrez Id: 5972
Gene Symbol: REN
REN
renin 0.370 0.923 2.4E-07
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.080 None 1.000 8 0 2001 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
C-reactive protein 0.299 0.962 3.7E-03
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.060 None 0.833 6 1 2012 2019
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
galectin 3 0.392 0.846 2.3E-05
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.050 None 1.000 5 0 2016 2018
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.367 0.923 5.0E-08
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.050 None 1.000 5 1 1996 2020
Entrez Id: 348
Gene Symbol: APOE
APOE
apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.050 None 0.600 4 0 2001 2017
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.050 None 1.000 4 0 1996 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.040 None 1.000 4 0 1997 2017
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B
TNF receptor superfamily member 11b 0.422 0.808 0.16
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.040 None 1.000 3 0 2004 2018
Entrez Id: 338
Gene Symbol: APOB
APOB
apolipoprotein B 0.453 0.808 1.9E-16
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.040 None 1.000 3 1 2001 2019
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
natriuretic peptide B 0.513 0.808 9.9E-06
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.040 None 1.000 2 0 2008 2018
Entrez Id: 2335
Gene Symbol: FN1
FN1
fibronectin 1 0.365 0.962 1.4E-03
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.030 None 1.000 3 0 2001 2011
Entrez Id: 4142
Gene Symbol: MAS1
MAS1
MAS1 proto-oncogene, G protein-coupled receptor 0.533 0.769 8.3E-05
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.030 None 0.667 3 0 2011 2019
Entrez Id: 54873
Gene Symbol: PALMD
PALMD
palmdelphin 0.931 0.115 3.4E-04
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.030 None 1.000 3 0 2018 2019
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.353 0.885 2.1E-06
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.030 None 1.000 3 0 1995 2017
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.030 None 1.000 3 0 2004 2019
Entrez Id: 6385
Gene Symbol: SDC4
SDC4
syndecan 4 0.603 0.615 4.1E-03
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.020 None 1.000 2 0 2011 2019