Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.353 0.885 2.1E-06
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.030 None 1.000 3 0 1995 2017
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.367 0.923 5.0E-08
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.050 None 1.000 5 1 1996 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.050 None 1.000 4 0 1996 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.040 None 1.000 4 0 1997 2017
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.318 0.885 0.27
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.020 None 1.000 2 0 1997 2017
Entrez Id: 2597
Gene Symbol: GAPDH
GAPDH
glyceraldehyde-3-phosphate dehydrogenase 0.447 0.808 0.11
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.010 None 1.000 1 0 1997 1997
Entrez Id: 5972
Gene Symbol: REN
REN
renin 0.370 0.923 2.4E-07
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.080 None 1.000 8 0 2001 2019
Entrez Id: 348
Gene Symbol: APOE
APOE
apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.050 None 0.600 4 0 2001 2017
Entrez Id: 338
Gene Symbol: APOB
APOB
apolipoprotein B 0.453 0.808 1.9E-16
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.040 None 1.000 3 1 2001 2019
Entrez Id: 2335
Gene Symbol: FN1
FN1
fibronectin 1 0.365 0.962 1.4E-03
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.030 None 1.000 3 0 2001 2011
Entrez Id: 7421
Gene Symbol: VDR
VDR
vitamin D receptor 0.352 0.885 1.7E-05
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.010 None 1.000 1 1 2001 2001
Entrez Id: 1585
Gene Symbol: CYP11B2
CYP11B2
cytochrome P450 family 11 subfamily B member 2 0.553 0.615 7.1E-19
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.010 None 1.000 1 0 2001 2001
Entrez Id: 4311
Gene Symbol: MME
MME
membrane metalloendopeptidase 0.407 0.808 1.5E-18
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.020 None 1.000 2 0 2002 2019
Entrez Id: 780
Gene Symbol: DDR1
DDR1
discoidin domain receptor tyrosine kinase 1 0.497 0.808 4.6E-06
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.010 None 1.000 1 0 2002 2002
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.010 None 1.000 1 0 2003 2003
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B
TNF receptor superfamily member 11b 0.422 0.808 0.16
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.040 None 1.000 3 0 2004 2018
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.030 None 1.000 3 0 2004 2019
Entrez Id: 3329
Gene Symbol: HSPD1
HSPD1
heat shock protein family D (Hsp60) member 1 0.432 0.808 0.99
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.010 None 1.000 1 0 2004 2004
Entrez Id: 5532
Gene Symbol: PPP3CB
PPP3CB
protein phosphatase 3 catalytic subunit beta 0.760 0.308 1.00
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.010 None 1.000 1 0 2004 2004
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.324 0.962 1.00
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.010 None 1.000 1 0 2004 2004
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.220 None 1.000 2 0 2005 2018
Entrez Id: 182
Gene Symbol: JAG1
JAG1
jagged canonical Notch ligand 1 0.429 0.808 1.00
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.010 None 1.000 1 0 2005 2005
Entrez Id: 4880
Gene Symbol: NPPC
NPPC
natriuretic peptide C 0.568 0.769 6.1E-02
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.220 None 1.000 2 0 2007 2019
Entrez Id: 6280
Gene Symbol: S100A9
S100A9
S100 calcium binding protein A9 0.433 0.885 0.48
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.010 None 1.000 1 0 2007 2007
Entrez Id: 28999
Gene Symbol: KLF15
KLF15
Kruppel like factor 15 0.592 0.654 0.49
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis
disease 0.010 None 1.000 1 0 2007 2007