Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
Identification of a novel CHEK2 variant and assessment of its contribution to the risk of breast cancer in French Canadian women.
|
18706089 |
2008 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
Effect of CHEK2 missense variant I157T on the risk of breast cancer in carriers of other CHEK2 or BRCA1 mutations.
|
18930998 |
2009 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
Pathology of breast cancer in women with constitutional CHEK2 mutations.
|
15803365 |
2005 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
Breast tumors which arise in carriers of CHEK2 mutations seem to be similar to those of breast cancers in the population at large.
|
16914568 |
2006 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
Breast cancer low-penetrance allele 1100delC in the CHEK2 gene: not present in the Chinese familial breast cancer population.
|
18484200 |
2008 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations.
|
11967536 |
2002 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
Analysis of CHEK2 FHA domain in Czech patients with sporadic breast cancer revealed distinct rare genetic alterations.
|
18058223 |
2008 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
Biomarker |
LHGDN |
Breast cancer survival and tumor characteristics in premenopausal women carrying the CHEK2*1100delC germline mutation.
|
17132695 |
2007 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
Tumour characteristics and prognosis of breast cancer patients carrying the germline CHEK2*1100delC variant.
|
15466005 |
2004 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
Absence of CHEK2 1100delC mutation in familial breast cancer cases from a South American population.
|
17876702 |
2008 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
Biomarker |
LHGDN |
CHEKs and balances: accounting for breast cancer.
|
11984555 |
2002 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
CHEK2*1100delC genotyping for clinical assessment of breast cancer risk: meta-analyses of 26,000 patient cases and 27,000 controls.
|
18172190 |
2008 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
Germline CHEK2 mutations in Jewish Ashkenazi women at high risk for breast cancer.
|
18085035 |
2007 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
CHEK2 1100delC is prevalent in Swedish early onset familial breast cancer.
|
17705858 |
2007 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
Finally, tissue microarray analysis indicated that breast tumors from patients with 1100delC mutations show reduced CHEK2 immunostaining.
|
12094328 |
2002 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
Linkage disequilibrium mapping of CHEK2: common variation and breast cancer risk.
|
16671833 |
2006 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
Functional and genomic approaches reveal an ancient CHEK2 allele associated with breast cancer in the Ashkenazi Jewish population.
|
15649950 |
2005 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts.
|
17721994 |
2007 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
Frequency of the CHEK2 1100delC mutation among women with breast cancer: an international study.
|
18381420 |
2008 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
Biomarker |
LHGDN |
The CHEK2 gene and inherited breast cancer susceptibility.
|
16998506 |
2006 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
The CHEK2 1100delC mutation is not present in Korean patients with breast cancer cases tested for BRCA1 and BRCA2 mutation.
|
18175216 |
2008 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
Biomarker |
LHGDN |
CHEK2*1100delC and susceptibility to breast cancer: a collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studies.
|
15122511 |
2004 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
Risk for contralateral breast cancer among carriers of the CHEK2*1100delC mutation in the WECARE Study.
|
18253122 |
2008 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
GeneticVariation |
LHGDN |
Increased risk of breast cancer associated with CHEK2*1100delC.
|
16880452 |
2007 |
Entrez Id: |
11200 |
Gene Symbol: |
CHEK2 |
CHEK2
|
Mammary Neoplasms
|
0.500 |
AlteredExpression |
LHGDN |
Expression of checkpoint kinase 2 in breast carcinomas: correlation with key regulators of tumor cell proliferation, angiogenesis, and survival.
|
16437383 |
2006 |