Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 133
Gene Symbol: ADM
ADM
CUI: C0018801
Disease: Heart failure
Heart failure
0.300 AlteredExpression LHGDN Cessation of pulmonary and coronary secretion of adrenomedullin peptides in the progression of human heart failure. 11972292

2002

Entrez Id: 11188
Gene Symbol: NISCH
NISCH
CUI: C0018801
Disease: Heart failure
Heart failure
0.010 AlteredExpression LHGDN Imidazoline receptors in the heart: characterization, distribution, and regulation. 12021582

2002

Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
CUI: C0018801
Disease: Heart failure
Heart failure
0.600 AlteredExpression LHGDN [Gene expression of Ang II receptors in myocardium in congestive heart failure]. 12133421

2002

Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
CUI: C0018801
Disease: Heart failure
Heart failure
0.230 AlteredExpression LHGDN [Gene expression of Ang II receptors in myocardium in congestive heart failure]. 12133421

2002

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0018801
Disease: Heart failure
Heart failure
0.600 AlteredExpression LHGDN [The effects of exercise training on plasma tumor necrosis factor-alpha, blood leucocyte and its components in congestive heart failure patients]. 12133434

2002

Entrez Id: 3572
Gene Symbol: IL6ST
IL6ST
CUI: C0018801
Disease: Heart failure
Heart failure
0.050 Biomarker LHGDN This study was designed to determine left ventricular expression of CT-1 and its glycoprotein 130 (gp130)/leukemia inhibitory factor receptor complex in human end-stage heart failure due to ischemic and dilated cardiomyopathy. 12234945

2002

Entrez Id: 1489
Gene Symbol: CTF1
CTF1
CUI: C0018801
Disease: Heart failure
Heart failure
0.050 AlteredExpression LHGDN This study was designed to determine left ventricular expression of CT-1 and its glycoprotein 130 (gp130)/leukemia inhibitory factor receptor complex in human end-stage heart failure due to ischemic and dilated cardiomyopathy. 12234945

2002

Entrez Id: 5744
Gene Symbol: PTHLH
PTHLH
CUI: C0018801
Disease: Heart failure
Heart failure
0.010 AlteredExpression LHGDN Parathyroid hormone-related protein is produced in the myocardium and increased in patients with congestive heart failure. 12364464

2002

Entrez Id: 7078
Gene Symbol: TIMP3
TIMP3
CUI: C0018801
Disease: Heart failure
Heart failure
0.020 AlteredExpression LHGDN We hypothesized that a reduction of myocardial TIMP-3 is associated with adverse matrix remodeling in both human and experimental heart failure. 12388270

2003

Entrez Id: 5350
Gene Symbol: PLN
PLN
CUI: C0018801
Disease: Heart failure
Heart failure
0.300 GeneticVariation LHGDN Transgenic PLN(R9C) mice recapitulated human heart failure with premature death. 12610310

2003

Entrez Id: 10911
Gene Symbol: UTS2
UTS2
CUI: C0018801
Disease: Heart failure
Heart failure
0.060 Biomarker LHGDN Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure. 12791592

2003

Entrez Id: 5468
Gene Symbol: PPARG
PPARG
CUI: C0018801
Disease: Heart failure
Heart failure
0.380 AlteredExpression LHGDN Although activation of PPARgamma appears to have beneficial effects on atherosclerosis and heart failure, it is still largely uncertain whether PPARgamma ligands prevent the development of cardiovascular diseases. 12861348

2003

Entrez Id: 8862
Gene Symbol: APLN
APLN
CUI: C0018801
Disease: Heart failure
Heart failure
0.300 AlteredExpression LHGDN Circulating and cardiac levels of apelin, the novel ligand of the orphan receptor APJ, in patients with heart failure. 12914775

2003

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0018801
Disease: Heart failure
Heart failure
0.600 Biomarker LHGDN TNFalpha in patients with congestive heart failure. 14685701

2004

Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
CUI: C0018801
Disease: Heart failure
Heart failure
0.400 AlteredExpression LHGDN Ischemic heart disease induces upregulation of endothelin receptor mRNA in human coronary arteries. 14729387

2004

Entrez Id: 1910
Gene Symbol: EDNRB
EDNRB
CUI: C0018801
Disease: Heart failure
Heart failure
0.340 AlteredExpression LHGDN Ischemic heart disease induces upregulation of endothelin receptor mRNA in human coronary arteries. 14729387

2004

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0018801
Disease: Heart failure
Heart failure
0.600 GeneticVariation LHGDN Effects of ACE gene insertion/deletion polymorphism on response to spironolactone in patients with chronic heart failure. 15121491

2004

Entrez Id: 359
Gene Symbol: AQP2
AQP2
CUI: C0018801
Disease: Heart failure
Heart failure
0.010 AlteredExpression LHGDN Urinary excretion of aquaporin-2 water channel exaggerated dependent upon vasopressin in congestive heart failure. 15458431

2004

Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
CUI: C0018801
Disease: Heart failure
Heart failure
0.300 GeneticVariation LHGDN Sodium channel mutations and susceptibility to heart failure and atrial fibrillation. 15671429

2005

Entrez Id: 133
Gene Symbol: ADM
ADM
CUI: C0018801
Disease: Heart failure
Heart failure
0.300 Biomarker LHGDN Collectively, these results support a protective role for increased AM in the cardiac hypertrophy and heart failure. 15974887

2005

Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
CUI: C0018801
Disease: Heart failure
Heart failure
0.300 GeneticVariation LHGDN Arg16/Gly beta2-adrenergic receptor polymorphism alters the cardiac output response to isometric exercise. 15994241

2005

Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C0018801
Disease: Heart failure
Heart failure
0.600 Biomarker LHGDN Differential role of TGF-beta1/bFGF and ET-1 in graft fibrosis in heart failure patients. 16095497

2005

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0018801
Disease: Heart failure
Heart failure
0.100 Biomarker LHGDN Differential role of TGF-beta1/bFGF and ET-1 in graft fibrosis in heart failure patients. 16095497

2005

Entrez Id: 2247
Gene Symbol: FGF2
FGF2
CUI: C0018801
Disease: Heart failure
Heart failure
0.020 Biomarker LHGDN Differential role of TGF-beta1/bFGF and ET-1 in graft fibrosis in heart failure patients. 16095497

2005

Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0018801
Disease: Heart failure
Heart failure
0.100 AlteredExpression LHGDN Elevated circulating levels of heat shock protein 70 are related to systemic inflammatory reaction through monocyte Toll signal in patients with heart failure after acute myocardial infarction. 16714144

2006