×
Entrez Id: 1636
Gene Symbol: ACE
ACE
Heart failure
0.600
AlteredExpression
LHGDN
Gene polymorphism of angiotensin-converting enzyme and angiotensin II type 1 receptor in patients with congestive heart failure.
18767410 2007
×
Entrez Id: 1636
Gene Symbol: ACE
ACE
Heart failure
0.600
GeneticVariation
LHGDN
Effects of ACE gene insertion/deletion polymorphism on response to spironolactone in patients with chronic heart failure.
15121491 2004
×
Entrez Id: 112
Gene Symbol: ADCY6
ADCY6
Heart failure
0.020
Biomarker
LHGDN
Adenylylcyclase gene transfer increases function of the failing heart.
17007567 2006
×
Entrez Id: 133
Gene Symbol: ADM
ADM
Heart failure
0.300
Biomarker
LHGDN
Collectively, these results support a protective role for increased AM in the cardiac hypertrophy and heart failure .
15974887 2005
×
Entrez Id: 133
Gene Symbol: ADM
ADM
Heart failure
0.300
AlteredExpression
LHGDN
Cessation of pulmonary and coronary secretion of adrenomedullin peptides in the progression of human heart failure .
11972292 2002
×
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
Heart failure
0.300
GeneticVariation
LHGDN
Arg16/Gly beta2-adrenergic receptor polymorphism alters the cardiac output response to isometric exercise.
15994241 2005
×
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
Heart failure
0.600
AlteredExpression
LHGDN
[Gene expression of Ang II receptors in myocardium in congestive heart failure].
12133421 2002
×
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
Heart failure
0.600
AlteredExpression
LHGDN
Gene polymorphism of angiotensin-converting enzyme and angiotensin II type 1 receptor in patients with congestive heart failure.
18767410 2007
×
Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
Heart failure
0.230
AlteredExpression
LHGDN
[Gene expression of Ang II receptors in myocardium in congestive heart failure].
12133421 2002
×
Entrez Id: 270
Gene Symbol: AMPD1
AMPD1
Heart failure
0.100
GeneticVariation
LHGDN
Association of C34T AMPD1 gene polymorphism with features of metabolic syndrome in patients with coronary artery disease or heart failure .
18855224 2009
×
Entrez Id: 8862
Gene Symbol: APLN
APLN
Heart failure
0.300
AlteredExpression
LHGDN
Circulating and cardiac levels of apelin , the novel ligand of the orphan receptor APJ, in patients with heart failure .
12914775 2003
×
Entrez Id: 359
Gene Symbol: AQP2
AQP2
Heart failure
0.010
AlteredExpression
LHGDN
Urinary excretion of aquaporin-2 water channel exaggerated dependent upon vasopressin in congestive heart failure.
15458431 2004
×
Entrez Id: 817
Gene Symbol: CAMK2D
CAMK2D
Heart failure
0.020
Biomarker
LHGDN
Nuclear calcium/calmodulin-dependent protein kinase IIdelta preferentially transmits signals to histone deacetylase 4 in cardiac cells.
17179159 2007
×
Entrez Id: 1489
Gene Symbol: CTF1
CTF1
Heart failure
0.050
AlteredExpression
LHGDN
This study was designed to determine left ventricular expression of CT-1 and its glycoprotein 130 (gp130)/leukemia inhibitory factor receptor complex in human end-stage heart failure due to ischemic and dilated cardiomyopathy.
12234945 2002
×
Entrez Id: 1843
Gene Symbol: DUSP1
DUSP1
Heart failure
0.020
AlteredExpression
LHGDN
Modulation of the p38MAPK pathway in failing human myocardium secondary to rheumatic heart disease.
18095520 2007
×
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
Heart failure
0.600
Biomarker
LHGDN
Differential role of TGF-beta1/bFGF and ET-1 in graft fibrosis in heart failure patients.
16095497 2005
×
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
Heart failure
0.400
AlteredExpression
LHGDN
Ischemic heart disease induces upregulation of endothelin receptor mRNA in human coronary arteries.
14729387 2004
×
Entrez Id: 1910
Gene Symbol: EDNRB
EDNRB
Heart failure
0.340
AlteredExpression
LHGDN
Ischemic heart disease induces upregulation of endothelin receptor mRNA in human coronary arteries.
14729387 2004
×
Entrez Id: 2247
Gene Symbol: FGF2
FGF2
Heart failure
0.020
Biomarker
LHGDN
Differential role of TGF-beta1/bFGF and ET-1 in graft fibrosis in heart failure patients.
16095497 2005
×
Entrez Id: 2697
Gene Symbol: GJA1
GJA1
Heart failure
0.100
AlteredExpression
LHGDN
Gap junction remodelling in human heart failure is associated with increased interaction of connexin43 with ZO-1.
18056766 2008
×
Entrez Id: 9759
Gene Symbol: HDAC4
HDAC4
Heart failure
0.030
Biomarker
LHGDN
These findings identify HDAC4 as a specific downstream substrate of CaMKIIdeltaB in cardiac cells and have broad applications for the signaling pathways leading to cardiac hypertrophy and heart failure .
17179159 2007
×
Entrez Id: 3586
Gene Symbol: IL10
IL10
Heart failure
0.280
AlteredExpression
LHGDN
We conducted this study to investigate the effects of fluvastatin therapy on plasma IL-10 cytokine concentration in patients with HF .
18923248 2008
×
Entrez Id: 3572
Gene Symbol: IL6ST
IL6ST
Heart failure
0.050
Biomarker
LHGDN
This study was designed to determine left ventricular expression of CT-1 and its glycoprotein 130 (gp130 )/leukemia inhibitory factor receptor complex in human end-stage heart failure due to ischemic and dilated cardiomyopathy.
12234945 2002
×
Entrez Id: 3757
Gene Symbol: KCNH2
KCNH2
Heart failure
0.020
Biomarker
LHGDN
Sphingolipid metabolite ceramide causes metabolic perturbation contributing to HERG K+ channel dysfunction.
17762170 2007
×
Entrez Id: 4015
Gene Symbol: LOX
LOX
Heart failure
0.070
Biomarker
LHGDN
Upregulation of lysyl oxidase and MMPs during cardiac remodeling in human dilated cardiomyopathy.
17849172 2008