×
Entrez Id: 7082
Gene Symbol: TJP1
TJP1
Heart failure
0.010
AlteredExpression
LHGDN
Gap junction remodelling in human heart failure is associated with increased interaction of connexin43 with ZO-1.
18056766 2008
×
Entrez Id: 359
Gene Symbol: AQP2
AQP2
Heart failure
0.010
AlteredExpression
LHGDN
Urinary excretion of aquaporin-2 water channel exaggerated dependent upon vasopressin in congestive heart failure.
15458431 2004
×
Entrez Id: 5744
Gene Symbol: PTHLH
PTHLH
Heart failure
0.010
AlteredExpression
LHGDN
Parathyroid hormone-related protein is produced in the myocardium and increased in patients with congestive heart failure.
12364464 2002
×
Entrez Id: 11188
Gene Symbol: NISCH
NISCH
Heart failure
0.010
AlteredExpression
LHGDN
Imidazoline receptors in the heart: characterization, distribution, and regulation.
12021582 2002
×
Entrez Id: 817
Gene Symbol: CAMK2D
CAMK2D
Heart failure
0.020
Biomarker
LHGDN
Nuclear calcium/calmodulin-dependent protein kinase IIdelta preferentially transmits signals to histone deacetylase 4 in cardiac cells.
17179159 2007
×
Entrez Id: 3757
Gene Symbol: KCNH2
KCNH2
Heart failure
0.020
Biomarker
LHGDN
Sphingolipid metabolite ceramide causes metabolic perturbation contributing to HERG K+ channel dysfunction.
17762170 2007
×
Entrez Id: 1843
Gene Symbol: DUSP1
DUSP1
Heart failure
0.020
AlteredExpression
LHGDN
Modulation of the p38MAPK pathway in failing human myocardium secondary to rheumatic heart disease.
18095520 2007
×
Entrez Id: 112
Gene Symbol: ADCY6
ADCY6
Heart failure
0.020
Biomarker
LHGDN
Adenylylcyclase gene transfer increases function of the failing heart.
17007567 2006
×
Entrez Id: 2247
Gene Symbol: FGF2
FGF2
Heart failure
0.020
Biomarker
LHGDN
Differential role of TGF-beta1/bFGF and ET-1 in graft fibrosis in heart failure patients.
16095497 2005
×
Entrez Id: 7078
Gene Symbol: TIMP3
TIMP3
Heart failure
0.020
AlteredExpression
LHGDN
We hypothesized that a reduction of myocardial TIMP-3 is associated with adverse matrix remodeling in both human and experimental heart failure .
12388270 2003
×
Entrez Id: 9759
Gene Symbol: HDAC4
HDAC4
Heart failure
0.030
Biomarker
LHGDN
These findings identify HDAC4 as a specific downstream substrate of CaMKIIdeltaB in cardiac cells and have broad applications for the signaling pathways leading to cardiac hypertrophy and heart failure .
17179159 2007
×
Entrez Id: 94025
Gene Symbol: MUC16
MUC16
Heart failure
0.040
Biomarker
LHGDN
Carbohydrate antigen 125 (CA 125 ), known as a tumor marker for ovarian cancer, has been reported to increase and relate to severity in heart failure patients with systolic dysfunction.
17285443 2007
×
Entrez Id: 3572
Gene Symbol: IL6ST
IL6ST
Heart failure
0.050
Biomarker
LHGDN
This study was designed to determine left ventricular expression of CT-1 and its glycoprotein 130 (gp130 )/leukemia inhibitory factor receptor complex in human end-stage heart failure due to ischemic and dilated cardiomyopathy.
12234945 2002
×
Entrez Id: 1489
Gene Symbol: CTF1
CTF1
Heart failure
0.050
AlteredExpression
LHGDN
This study was designed to determine left ventricular expression of CT-1 and its glycoprotein 130 (gp130)/leukemia inhibitory factor receptor complex in human end-stage heart failure due to ischemic and dilated cardiomyopathy.
12234945 2002
×
Entrez Id: 10911
Gene Symbol: UTS2
UTS2
Heart failure
0.060
Biomarker
LHGDN
Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure.
12791592 2003
×
Entrez Id: 4015
Gene Symbol: LOX
LOX
Heart failure
0.070
Biomarker
LHGDN
Upregulation of lysyl oxidase and MMPs during cardiac remodeling in human dilated cardiomyopathy.
17849172 2008
×
Entrez Id: 270
Gene Symbol: AMPD1
AMPD1
Heart failure
0.100
GeneticVariation
LHGDN
Association of C34T AMPD1 gene polymorphism with features of metabolic syndrome in patients with coronary artery disease or heart failure .
18855224 2009
×
Entrez Id: 2697
Gene Symbol: GJA1
GJA1
Heart failure
0.100
AlteredExpression
LHGDN
Gap junction remodelling in human heart failure is associated with increased interaction of connexin43 with ZO-1.
18056766 2008
×
Entrez Id: 4607
Gene Symbol: MYBPC3
MYBPC3
Heart failure
0.100
Biomarker
LHGDN
Myosin binding protein C phosphorylation in normal, hypertrophic and failing human heart muscle.
18573260 2008
×
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
Heart failure
0.100
AlteredExpression
LHGDN
Modulation of the p38MAPK pathway in failing human myocardium secondary to rheumatic heart disease.
18095520 2007
×
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
Heart failure
0.100
AlteredExpression
LHGDN
Elevated circulating levels of heat shock protein 70 are related to systemic inflammatory reaction through monocyte Toll signal in patients with heart failure after acute myocardial infarction.
16714144 2006
×
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
Heart failure
0.100
Biomarker
LHGDN
Differential role of TGF-beta1 /bFGF and ET-1 in graft fibrosis in heart failure patients.
16095497 2005
×
Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
Heart failure
0.230
AlteredExpression
LHGDN
[Gene expression of Ang II receptors in myocardium in congestive heart failure].
12133421 2002
×
Entrez Id: 4625
Gene Symbol: MYH7
MYH7
Heart failure
0.250
Biomarker
LHGDN
Sarcomere protein gene mutations and inherited heart disease: a beta-cardiac myosin heavy chain mutation causing endocardial fibroelastosis and heart failure.
17019812 2006
×
Entrez Id: 3586
Gene Symbol: IL10
IL10
Heart failure
0.280
AlteredExpression
LHGDN
We conducted this study to investigate the effects of fluvastatin therapy on plasma IL-10 cytokine concentration in patients with HF .
18923248 2008