×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Rheumatoid arthritis patients showed high TNFalpha mRNA expression (1.33-fold).18797411 2008
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus.
15641066 2005
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis.
15208781 2004
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Auto-antibodies, HLA and PTPN22: susceptibility markers for rheumatoid arthritis.
18156150 2008
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Could single-nucleotide polymorphisms (SNPs) affecting the tumour necrosis factor promoter be considered as part of rheumatoid arthritis evolution?
16446172 2006
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
The PTPN22 promoter polymorphism -1123G>C association cannot be distinguished from the 1858C>T association in a Norwegian rheumatoid arthritis material.
17661906 2007
×
Entrez Id: 6583
Gene Symbol: SLC22A4
SLC22A4
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Replication of reported genetic associations of PADI4, FCRL3, SLC22A4 and RUNX1 genes with rheumatoid arthritis: results of an independent Japanese population and evidence from meta-analysis of East Asian studies.
18087673 2008
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis.
17436241 2007
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
PTPN22 polymorphism and anti-cyclic citrullinated peptide antibodies in combination strongly predicts future onset of rheumatoid arthritis and has a specificity of 100% for the disease.
16507117 2006
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Tumor necrosis factor-alpha -308 promoter polymorphism contributes independently to HLA alleles in the severity of rheumatoid arthritis in Mexicans.
15725578 2005
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Association of R602W in a protein tyrosine phosphatase gene with a high risk of rheumatoid arthritis in a British population: evidence for an early onset/disease severity effect.
15641088 2005
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Polymorphism in the tumor necrosis factor-alpha gene promoter is associated with severity of rheumatoid arthritis in the Czech population.
17562093 2008
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Tumour necrosis factor (TNF)alpha -308 G/G promoter polymorphism and TNFalpha levels correlate with a better response to adalimumab in patients with rheumatoid arthritis.
17343250 2007
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
The 620W allele is the PTPN22 genetic variant conferring susceptibility to RA in a Dutch population.
17135225 2007
×
Entrez Id: 6583
Gene Symbol: SLC22A4
SLC22A4
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.
14608356 2003
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Rheumatoid arthritis seropositive for the rheumatoid factor is linked to the protein tyrosine phosphatase nonreceptor 22-620W allele.
16277672 2005
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Susceptibility for and clinical manifestations of rheumatoid arthritis are associated with polymorphisms of the TNF-alpha, IL-1beta, and IL-1Ra genes.
11838837 2002
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients.
16635271 2006
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Finnish case-control and family studies support PTPN22 R620W polymorphism as a risk factor in rheumatoid arthritis, but suggest only minimal or no effect in juvenile idiopathic arthritis.
16107870 2005
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Association of PTPN22 with rheumatoid arthritis among South Asians in the UK.
17696275 2007
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
TNF microsatellites polymorphism is associated with rheumatoid arthritis. Confirming evidence in northwestern Colombians.
17631742 2007
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Association of PTPN22 single nucleotide polymorphism with rheumatoid arthritis but not with allergic asthma.
17579671 2007
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Investigation of genetic variation across the protein tyrosine phosphatase gene in patients with rheumatoid arthritis in the UK.
17170052 2007
×
Entrez Id: 6583
Gene Symbol: SLC22A4
SLC22A4
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
No influence of SLC22A4 C6607T and RUNX1 G24658C genotypic variants on the circulating carnitine ester profile in patients with rheumatoid arthritis.
18328148 2008
×
Entrez Id: 6583
Gene Symbol: SLC22A4
SLC22A4
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
SLC22A4 polymorphism and rheumatoid arthritis susceptibility: a replication study in a Japanese population and a metaanalysis.
18709696 2008