Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 176
Gene Symbol: ACAN
ACAN
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.400 GeneticVariation LHGDN Association between the aggrecan gene and rheumatoid arthritis. 19004047

2008

Entrez Id: 54
Gene Symbol: ACP5
ACP5
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.030 Biomarker LHGDN Serum tartrate-resistant acid phosphatase isoforms in rheumatoid arthritis. 11983200

2002

Entrez Id: 54
Gene Symbol: ACP5
ACP5
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.030 Biomarker LHGDN Significance of serum TRACP in rheumatoid arthritis. 18410226

2008

Entrez Id: 9507
Gene Symbol: ADAMTS4
ADAMTS4
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.050 AlteredExpression LHGDN Expression and regulation of aggrecanase in arthritis: the role of TGF-beta. 11801682

2002

Entrez Id: 11096
Gene Symbol: ADAMTS5
ADAMTS5
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.030 AlteredExpression LHGDN Expression and regulation of aggrecanase in arthritis: the role of TGF-beta. 11801682

2002

Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.400 Biomarker LHGDN Adiponectin stimulates IL-8 production by rheumatoid synovial fibroblasts. 19013427

2009

Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.400 AlteredExpression LHGDN Insulin resistance and adiponectin levels in Behçet's syndrome. 17949565

2008

Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.400 AlteredExpression LHGDN High-grade inflammation, circulating adiponectin concentrations and cardiovascular risk factors in severe rheumatoid arthritis. 18799090

2009

Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.050 Biomarker LHGDN beta2-adrenergic receptor gene single-nucleotide polymorphisms are associated with rheumatoid arthritis in northern Sweden. 15794198

2004

Entrez Id: 155
Gene Symbol: ADRB3
ADRB3
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.010 GeneticVariation LHGDN Polymorphism of the beta3-adrenergic receptor and lipid profile in patients with rheumatoid arthritis and systemic lupus erythematosus treated with chloroquine. 12739037

2003

Entrez Id: 177
Gene Symbol: AGER
AGER
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.470 AlteredExpression LHGDN RAGE activation induces invasiveness of RA fibroblast-like synoviocytes in vitro. 18078623

2008

Entrez Id: 177
Gene Symbol: AGER
AGER
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.470 GeneticVariation LHGDN RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response. 12070776

2002

Entrez Id: 177
Gene Symbol: AGER
AGER
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.470 Biomarker LHGDN Serum amyloid A activates nuclear factor-kappaB in rheumatoid synovial fibroblasts through binding to receptor of advanced glycation end-products. 18322992

2008

Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.160 GeneticVariation LHGDN Association of allograft inflammatory factor-1 gene polymorphism with rheumatoid arthritis. 18721278

2008

Entrez Id: 270
Gene Symbol: AMPD1
AMPD1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.010 Biomarker LHGDN Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent-onset rheumatoid arthritis. 16947783

2006

Entrez Id: 301
Gene Symbol: ANXA1
ANXA1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.040 AlteredExpression LHGDN Annexin-1 modulates T-cell activation and differentiation. 17008549

2007

Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.050 GeneticVariation LHGDN Evaluation of lipid profile, macular toxicity and clinical manifestations according to APO E genotype in systemic lupus erythematosus and rheumatoid arthritis patients treated with chloroquine. 11922198

2002

Entrez Id: 471
Gene Symbol: ATIC
ATIC
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.340 GeneticVariation LHGDN Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis. 15457444

2004

Entrez Id: 476
Gene Symbol: ATP1A1
ATP1A1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.010 AlteredExpression LHGDN Serum E-selectin and erythrocyte membrane Na+K+ ATPase levels in patients with rheumatoid arthritis. 15515123

2005

Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.100 AlteredExpression LHGDN Fibroblast-like synoviocytes from rheumatoid arthritis patients express functional IL-15 receptor complex: endogenous IL-15 in autocrine fashion enhances cell proliferation and expression of Bcl-x(L) and Bcl-2. 12165497

2002

Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.010 AlteredExpression LHGDN Bcl-x(L) expression in vivo in rheumatoid synovium. 16572289

2006

Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.020 AlteredExpression LHGDN Pathological survivin expression links viral infections with pathogenesis of erosive rheumatoid arthritis. 17635796

2007

Entrez Id: 652
Gene Symbol: BMP4
BMP4
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.320 AlteredExpression LHGDN Decrease in expression of bone morphogenetic proteins 4 and 5 in synovial tissue of patients with osteoarthritis and rheumatoid arthritis. 16542506

2006

Entrez Id: 653
Gene Symbol: BMP5
BMP5
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.010 AlteredExpression LHGDN Decrease in expression of bone morphogenetic proteins 4 and 5 in synovial tissue of patients with osteoarthritis and rheumatoid arthritis. 16542506

2006

Entrez Id: 660
Gene Symbol: BMX
BMX
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis
0.010 Biomarker LHGDN Etk/BMX, a Btk family tyrosine kinase, and Mal contribute to the cross-talk between MyD88 and FAK pathways. 18292575

2008