|
rs1344706
|
|
Schizophrenia
|
|
0.900 |
GeneticVariation
|
BEFREE |
Neither univariate nor multivariate analyses showed any associations between indices of grey matter and rs1344706 variation in schizophrenia or healthy participants.
|
29247760 |
2018 |
|
rs1344706
|
|
Schizophrenia
|
|
0.900 |
GeneticVariation
|
BEFREE |
In light of the strong DTI evidence for white matter microstructural abnormalities in schizophrenia, the current results implicate a potential mechanism for schizophrenia risk formation by ZNF804A rs1344706 genotype.
|
24685285 |
2014 |
|
rs1344706
|
|
Schizophrenia
|
|
0.900 |
GeneticVariation
|
BEFREE |
Its intronic single-nucleotide polymorphism (SNP) rs1344706 is among one of the strongest susceptibility variants that have achieved genome-wide significance in genome-wide association studies (GWAS) for schizophrenia and has been widely and intensively studied.
|
28289284 |
2017 |
|
rs1344706
|
|
Schizophrenia
|
|
0.900 |
GeneticVariation
|
BEFREE |
Although significant main effects of the diagnosis of schizophrenia were found on radial diffusivity, no association between the ZNF804A (rs1344706) and white matter connectivity was found in the entire group of subjects or in a selected subgroup of age-matched subjects (n=72).
|
23147122 |
2013 |
|
rs1344706
|
|
Schizophrenia
|
|
0.900 |
GeneticVariation
|
BEFREE |
Association analysis of ZNF804A (zinc finger protein 804A) rs1344706 with therapeutic response to atypical antipsychotics in first-episode Chinese patients with schizophrenia.
|
22425527 |
2012 |
|
rs1344706
|
|
Schizophrenia
|
|
0.900 |
GeneticVariation
|
BEFREE |
The only in vivo endophenotype study of the SZ-associated SNP (rs1344706) pointed towards effects on brain functional connectivity.
|
20664580 |
2010 |
|
rs1344706
|
|
Schizophrenia
|
|
0.900 |
GeneticVariation
|
BEFREE |
Furthermore, we performed a four-SNP haplotype analysis which included the SNPs from the three-SNP haplotype analysis and rs1344706 (global P = 0.0005), and found that haplotype GCCG was associated with schizophrenia (P = 0.003).
|
21993378 |
2011 |
|
rs1344706
|
|
Schizophrenia
|
|
0.900 |
GeneticVariation
|
BEFREE |
Three SNPs (rs1625579, rs1344706 and rs4765905) showed a consistent direction of effect with previous studies and the polygenic risk score constructed using the weighted sum of these three SNPs showed a significant association with Schizophrenia in this population (OR=3.78, p=0.005).
|
29599094 |
2018 |
|
rs1344706
|
|
Schizophrenia
|
|
0.900 |
GeneticVariation
|
BEFREE |
ZNF804a was identified by a genome-wide association study (GWAS) in which a single nucleotide polymorphism (SNP rs1344706) in ZNF804a reached genome-wide statistical significance for association with a combined diagnosis of schizophrenia (SZ) and bipolar disorder.
|
22384243 |
2012 |
|
rs1344706
|
|
Schizophrenia
|
|
0.900 |
GeneticVariation
|
BEFREE |
Previous studies indicated that single-nucleotide polymorphism (SNP) rs1344706 in ZNF804A was strongly associated with schizophrenia and might influence social interaction.
|
31122238 |
2019 |
|
rs1344706
|
|
Schizophrenia
|
|
0.900 |
GeneticVariation
|
BEFREE |
Our results elucidated the contribution of rs1344706 to functional connectivity within the brain network, and may have important implications for our understanding of this risk gene's role in functional dysconnectivity in schizophrenia.
|
29527501 |
2018 |
|
rs1344706
|
|
Schizophrenia
|
|
0.900 |
GeneticVariation
|
BEFREE |
Recent evidence indicated that the ZNF804A (rs1344706) risk allele A is associated with better cognitive performance in patients with schizophrenia.
|
24078172 |
2014 |
|
rs1344706
|
|
Schizophrenia
|
T |
0.900 |
GeneticVariation
|
GWASCAT |
Identification of loci associated with schizophrenia by genome-wide association and follow-up.
|
18677311 |
2008 |
|
rs1344706
|
|
Schizophrenia
|
T |
0.900 |
GeneticVariation
|
GWASDB |
Identification of loci associated with schizophrenia by genome-wide association and follow-up.
|
18677311 |
2008 |