|
rs833061
|
|
Age related macular degeneration
|
|
0.060 |
GeneticVariation
|
BEFREE |
However, weak correlations between 10 SNPs (CFH rs1329428 TT genotype, CFH rs3753394 CC genotype and T allele, CFH rs1410996 AA genotype, CFH rs800292 AA genotype, CFH rs800292 A allele, VEGF rs833061 TT genotype and C allele, VEGF rs2010963 CG genotype, VEGFR2 rs1531289 TT genotype, ARMS2 rs10490924 TT genotype, KCTD10 rs238104 GC genotype, rs1531289 T allele and ARMS2 rs10490924 T allele) and AMD were shown.
|
30696427 |
2019 |
|
rs833061
|
|
Age related macular degeneration
|
|
0.060 |
GeneticVariation
|
BEFREE |
Significant associations with AMD risk were showed for rs833061, rs1413711, and rs3025039 polymorphisms but not for rs2010963.
|
27999450 |
2016 |
|
rs833061
|
|
Age related macular degeneration
|
|
0.060 |
GeneticVariation
|
BEFREE |
The meta-analysis results based on nine case-control studies with 2427 cases and 2037 controls showed that rs833061 had protective effects on AMD risk (TT vs. CT+CC: OR=0.58, 95% CI=0.41-0.81), whereas rs1413711 (TT vs. CT+CC: OR=1.46, 95% CI=1.10-1.93) and rs3025039 (TT vs. CC: OR=1.87, 95% CI=1.15-3.02; TT vs. CT+CC: OR=2.09, 95% CI=1.30-3.37) represented as risk factors for AMD.
|
24689893 |
2014 |
|
rs833061
|
|
Age related macular degeneration
|
|
0.060 |
GeneticVariation
|
BEFREE |
Our study shows that VEGFA rs699947 and rs833061 and VEGFR2 rs2071559 polymorphisms do not modify the risk of suffering AMD in a Spanish population.
|
23971975 |
2013 |
|
rs833061
|
|
Age related macular degeneration
|
|
0.060 |
GeneticVariation
|
BEFREE |
The results suggest the VEGF-A rs1413711 and rs833061 polymorphisms may contribute to AMD susceptibility.
|
23761723 |
2013 |
|
rs833061
|
|
Age related macular degeneration
|
|
0.060 |
GeneticVariation
|
BEFREE |
In our work, we searched for an association between the -460C> (rs833061) and -634G>C (rs2010963) polymorphisms of the VEGF gene and the occurrence of AMD and its dry and wet forms.
|
19761764 |
2009 |
|
rs833061
|
|
Psoriasis
|
|
0.040 |
GeneticVariation
|
BEFREE |
In addition, genetic complement, comprising the PGF rs2268615 AA genotype and the VEGFA -460 (rs833061) T allele, was significantly associated with the development of early-onset psoriasis (P < 0.03).
|
31545526 |
2020 |
|
rs833061
|
|
Psoriasis
|
|
0.040 |
GeneticVariation
|
BEFREE |
An association was found between rs1800629 (TNF-α) and Type I psoriasis, and rs833061 (VEGF) and Type II psoriasis.
|
31148856 |
2020 |
|
rs833061
|
|
Diabetic Retinopathy
|
|
0.040 |
GeneticVariation
|
BEFREE |
The T allele in rs3025039 and the C allele in rs833061 are associated with increased DR susceptibility.
|
27613596 |
2017 |
|
rs833061
|
|
Psoriasis
|
|
0.040 |
GeneticVariation
|
BEFREE |
Our results indicate that VEGF (rs2010963) polymorphism and CTC haplotype of the VEGF SNPs (rs699947, rs833061, and rs2010963) confer an increased risk of psoriasis in the South Indian Tamil population.
|
28803785 |
2017 |
|
rs833061
|
|
Diabetic Retinopathy
|
|
0.040 |
GeneticVariation
|
BEFREE |
After adjustment for covariates, significant association of DR remained with the homozygous genotype of the minor allele for the SNPs rs699947 (odds ratio [OR] = 3.54, 95% confidence interval [CI]: 1.12-11.19), rs833061 (OR = 3.72, 95% CI: 1.17-11.85), rs13207351 (OR = 3.76, 95% CI: 1.21-11.71), and rs2146323 (OR = 2.8, 95% CI: 1.46-5.37) in the VEGF gene as well as the SNP rs2071559 (OR = 1.62, 95% CI: 1.08-2.41) in the KDR gene.
|
24623964 |
2014 |
|
rs833061
|
|
Psoriasis
|
|
0.040 |
GeneticVariation
|
BEFREE |
The aim of this meta-analysis was to investigate large-scale evidence to determine the degree to which four common VEGF polymorphisms (+405C>G [dbSNP: rs2010963], -460T>C [dbSNP: rs833061], -2578C>A [dbSNP: rs699947], and -1154G>A [dbSNP: rs1570360]) are associated with susceptibility to psoriasis.
|
24678886 |
2014 |
|
rs833061
|
|
Diabetic Retinopathy
|
|
0.040 |
GeneticVariation
|
BEFREE |
A significant relationship between VEGF+936C/T (rs3025039) polymorphism and DR was found in a recessive model (OR = 3.19, 95% CI = 1.20-8.41, and P(z) = 0.01) in Asian and overall populations, while a significant association was also found between -460T/C (rs833061) polymorphism and DR risk under a recessive model (OR = 2.12, 95% CI = 1.12-4.01, and P(z) = 0.02).CONCLUSIONS.
|
24868559 |
2014 |
|
rs833061
|
|
Diabetic Retinopathy
|
|
0.040 |
GeneticVariation
|
BEFREE |
After adjusting for covariates, a significant association of DR was observed with the homozygous genotype of the minor allele for promoter SNPs rs699947 (odds ratio (OR)=3.54, 95% confidence interval (CI): 1.12-11.19), rs833061 (OR=3.72, 95% CI: 1.17-11.85) and rs13207351 (OR=3.76, 95% CI: 1.21-11.71).
|
22162628 |
2011 |
|
rs833061
|
|
Carcinoma of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
HIF2A rs13419896 and VEGFA rs833061 were significantly related to lung cancer risk, with possible interaction between polymorphisms and cigarette smoking.
|
27981753 |
2017 |
|
rs833061
|
|
Malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
HIF2A rs13419896 and VEGFA rs833061 were significantly related to lung cancer risk, with possible interaction between polymorphisms and cigarette smoking.
|
27981753 |
2017 |
|
rs833061
|
|
Primary malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
HIF2A rs13419896 and VEGFA rs833061 were significantly related to lung cancer risk, with possible interaction between polymorphisms and cigarette smoking.
|
27981753 |
2017 |
|
rs833061
|
|
Neoplasms
|
|
0.030 |
GeneticVariation
|
BEFREE |
Variant genotypes of rs833061 (TC + CC) were significantly associated with high-grade (G2 + G3) tumors (OR = 1.79; 95% CI = 1.12 - 2.84) and with positive lymph node status (OR = 1.34; 95% CI = 1.01 - 1.77), but showed no independent effect on disease-free survival.
|
27195611 |
2016 |
|
rs833061
|
|
Neoplasms
|
|
0.030 |
GeneticVariation
|
BEFREE |
However, when the patients were stratified by tumor histology, squamous cell carcinoma (SCC) and adenocarcinoma (AC) had significantly different OS (Adjusted hazard ratio [aHR] = 0.76, 95% CI = 0.56-1.03 in SCC; aHR = 1.33, 95% CI = 0.98-1.82 in AC; P for heterogeneity = 0.01) and DFS (aHR = 0.75, 95% CI = 0.58-0.97 in SCC; aHR = 1.26, 95% CI = 1.00-1.60 in AC; P for heterogeneity = 0.004) according to the rs833061T>C genotypes.
|
27709850 |
2016 |
|
rs833061
|
|
Carcinoma of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
rs833061 and rs699947 on promoter gene of vascular endothelial growth factor (VEGF) and associated lung cancer susceptibility and survival: a meta-analysis.
|
25468805 |
2014 |
|
rs833061
|
|
Primary malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
The aim of this meta-analysis is to generate large-scale evidence on whether common vascular endothelial growth factor (VEGF) gene polymorphisms (-2578C/A [dbSNP: rs699947] and -460C/T [dbSNP: rs833061]) are associated with lung cancer.
|
23982876 |
2014 |
|
rs833061
|
|
Carcinoma of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
The aim of this meta-analysis is to generate large-scale evidence on whether common vascular endothelial growth factor (VEGF) gene polymorphisms (-2578C/A [dbSNP: rs699947] and -460C/T [dbSNP: rs833061]) are associated with lung cancer.
|
23982876 |
2014 |
|
rs833061
|
|
Malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
rs833061 and rs699947 on promoter gene of vascular endothelial growth factor (VEGF) and associated lung cancer susceptibility and survival: a meta-analysis.
|
25468805 |
2014 |
|
rs833061
|
|
Primary malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
rs833061 and rs699947 on promoter gene of vascular endothelial growth factor (VEGF) and associated lung cancer susceptibility and survival: a meta-analysis.
|
25468805 |
2014 |
|
rs833061
|
|
Malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
The aim of this meta-analysis is to generate large-scale evidence on whether common vascular endothelial growth factor (VEGF) gene polymorphisms (-2578C/A [dbSNP: rs699947] and -460C/T [dbSNP: rs833061]) are associated with lung cancer.
|
23982876 |
2014 |