Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.160 None 1.000 17 5 2004 2019
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 444 0.412 0.885 1.2E-07 0.100 None 1.000 16 0 1999 2013
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
Q9NQB0 transcription factor 7 like 2 257 0.485 0.846 1.00 0.490 None 1.000 15 2 2002 2019
Entrez Id: 101805488
Gene Symbol: CCAT2
CCAT2
colon cancer associated transcript 2 56 0.621 0.615 0.100 None 1.000 14 3 2007 2019
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
P22897 mannose receptor C-type 1 431 0.413 0.846 0.94 0.100 None 0.929 14 0 1999 2017
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
P01344 insulin like growth factor 2 604 0.390 0.885 4.4E-02 0.400 None 1.000 13 0 1990 2017
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
P09237 matrix metallopeptidase 7 Enzyme 320 0.446 0.885 1.0E-09 0.100 None 0.923 13 0 1994 2014
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.400 None 1.000 13 1 1999 2014
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.200 None 1.000 12 7 2002 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.100 None 1.000 12 0 1997 2015
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 1.000 12 0 2003 2019
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 711 0.363 0.962 2.4E-07 0.100 None 1.000 12 0 1993 2015
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
P06731 CEA cell adhesion molecule 5 428 0.420 0.846 4.2E-10 0.100 None 1.000 11 0 1990 2014
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.400 None 1.000 11 0 1996 2018
Entrez Id: 10
Gene Symbol: NAT2
NAT2
P11245 N-acetyltransferase 2 Enzyme 311 0.451 0.885 3.3E-06 0.100 None 1.000 10 0 1996 2008
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
P38936 cyclin dependent kinase inhibitor 1A 490 0.403 0.769 1.9E-03 0.100 None 1.000 10 0 1996 2008
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.100 None 1.000 10 0 2003 2018
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 594 0.380 0.846 0.97 0.100 None 1.000 10 0 1995 2013
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.390 None 1.000 10 0 1990 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.410 None 1.000 10 6 2006 2016
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.100 None 1.000 10 0 1996 2008
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.390 None 1.000 10 0 2003 2017
Entrez Id: 120376
Gene Symbol: COLCA2
COLCA2
A8K830 colorectal cancer associated 2 12 0.769 0.154 0.75 0.100 None 1.000 9 2 2008 2019
Entrez Id: 1630
Gene Symbol: DCC
DCC
P43146 DCC netrin 1 receptor 279 0.471 0.808 0.99 0.380 None 1.000 9 1 1992 2007
Entrez Id: 1890
Gene Symbol: TYMP
TYMP
P19971 thymidine phosphorylase Enzyme 246 0.495 0.769 1.2E-04 0.370 None 1.000 9 0 1998 2007