Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.320 GeneticVariation disease BEFREE This is the first study that associated 5-HT1A receptor promoter gene variants with stressors preceding the need of hospitalization for bipolar depression. 21397953 2011
Entrez Id: 27185
Gene Symbol: DISC1
DISC1 		0.310 Biomarker disease PSYGENET Disrupted in Schizophrenia 1 (DISC1) is a key susceptibility gene implicated in major mental illnesses, such as schizophrenia, depression, bipolar disorder and autism, but the link between this protein and the pathology of these diseases remains unclear. 22291444 2012
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2 		0.310 Biomarker disease BEFREE Here, we measured serum levels of tPA, plasminogen activator inhibitor-1 (PAI-1), BDNF, precursor-BDNF (proBDNF), tropomyosin-related kinase B (TrkB) and neurotrophin receptor p75 (p75NTR) in patients with paranoid schizophrenia (SZ, n = 34), MDD (n = 30), bipolar mania (BM, n = 30), bipolar depression (BD, n = 22), panic disorder (PD, n = 30), and healthy controls (HCs, n = 30) by Enzyme-linked immunosorbent assay kits. 28761093 2017
Entrez Id: 27185
Gene Symbol: DISC1
DISC1 		0.310 Biomarker disease BEFREE Disrupted in Schizophrenia 1 (DISC1) is a key susceptibility gene implicated in major mental illnesses, such as schizophrenia, depression, bipolar disorder and autism, but the link between this protein and the pathology of these diseases remains unclear. 22291444 2012
Entrez Id: 7466
Gene Symbol: WFS1
WFS1 		0.310 AlteredExpression disease BEFREE We also quantified the expression levels of WFS1 mRNA in the postmortem brains of patients with bipolar disorder, depression, schizophrenia, and controls. 12565131 2003
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C 		0.310 Biomarker disease CTD_human Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. 18711365 2008
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C 		0.310 GeneticVariation disease BEFREE Genetic variation in CACNA1C, which codes for the L-type calcium channel (LTCC) Ca<sub>v</sub> 1.2, is associated with clinical diagnoses of bipolar disorder, depression and schizophrenia. 28186690 2017
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B 		0.310 GeneticVariation disease BEFREE Glycogen synthase kinase 3 beta gene structural variants as possible risk factors of bipolar depression. 24677591 2014
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C 		0.310 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C 		0.310 Biomarker disease CTD_human Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. 21926972 2011
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2 		0.310 Biomarker disease CTD_human Association studies of the BDNF and the NTRK2 gene polymorphisms with prophylactic lithium response in bipolar patients. 19018715 2008
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B 		0.310 Biomarker disease CTD_human Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. 20357757 2010
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C 		0.310 Biomarker disease CTD_human Genome-wide association study identifies five new schizophrenia loci. 21926974 2011
Entrez Id: 6671
Gene Symbol: SP4
SP4 		0.300 Biomarker disease CTD_human Transcription factor SP4 is a susceptibility gene for bipolar disorder. 19401786 2009
Entrez Id: 10815
Gene Symbol: CPLX1
CPLX1 		0.300 Biomarker disease CTD_human Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. 14708030 2004
Entrez Id: 5091
Gene Symbol: PC
PC 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 5443
Gene Symbol: POMC
POMC 		0.300 Biomarker disease CTD_human Hypomanic reactions to ACTH and prednisone treatment for multiple sclerosis. 2843795 1988
Entrez Id: 4914
Gene Symbol: NTRK1
NTRK1 		0.300 Biomarker disease CTD_human Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. 14708030 2004
Entrez Id: 57519
Gene Symbol: STARD9
STARD9 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 51177
Gene Symbol: PLEKHO1
PLEKHO1 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 7222
Gene Symbol: TRPC3
TRPC3 		0.300 Biomarker disease CTD_human Chronic oxidative stress modulates TRPC3 and TRPM2 channel expression and function in rat primary cortical neurons: relevance to the pathophysiology of bipolar disorder. 23602965 2013
Entrez Id: 776
Gene Symbol: CACNA1D
CACNA1D 		0.300 Biomarker disease CTD_human Enhancing VTA Cav1.3 L-type Ca2+ channel activity promotes cocaine and mood-related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens. 28194001 2017
Entrez Id: 1812
Gene Symbol: DRD1
DRD1 		0.300 Biomarker disease CTD_human Dopamine D1 receptor gene polymorphism is associated with prophylactic lithium response in bipolar disorder. 19153942 2009
Entrez Id: 51650
Gene Symbol: MRPS33
MRPS33 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 22941
Gene Symbol: SHANK2
SHANK2 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019