Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7133
Gene Symbol: TNFRSF1B
TNFRSF1B 		0.010 Biomarker disease BEFREE Here, we measured serum levels of tPA, plasminogen activator inhibitor-1 (PAI-1), BDNF, precursor-BDNF (proBDNF), tropomyosin-related kinase B (TrkB) and neurotrophin receptor p75 (p75NTR) in patients with paranoid schizophrenia (SZ, n = 34), MDD (n = 30), bipolar mania (BM, n = 30), bipolar depression (BD, n = 22), panic disorder (PD, n = 30), and healthy controls (HCs, n = 30) by Enzyme-linked immunosorbent assay kits. 28761093 2017
Entrez Id: 5715
Gene Symbol: PSMD9
PSMD9 		0.010 GeneticVariation disease BEFREE PSMD9 is located in the chromosome 12q24 locus, which per se is in linkage with depression, bipolar disorder and anxiety. 24648162 2014
Entrez Id: 5463
Gene Symbol: POU6F1
POU6F1 		0.010 Biomarker disease BEFREE Brain 5-HT1A binding potential (BP(F) = B(max)/K(D), where B(max) = total available receptors, and 1/K(D) = ligand affinity) was measured in 32 currently depressed, medication-free BD subjects and 47 controls. 19278673 2009
Entrez Id: 2670
Gene Symbol: GFAP
GFAP 		0.010 AlteredExpression disease BEFREE Glial fibrillary acidic protein mRNA levels in the cingulate cortex of individuals with depression, bipolar disorder and schizophrenia. 15885920 2005
Entrez Id: 1813
Gene Symbol: DRD2
DRD2 		0.010 GeneticVariation disease BEFREE Dopamine receptor D2 and D3 gene variants are not associated with the antidepressant effect of total sleep deprivation in bipolar depression. 12834818 2003
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.020 Biomarker disease BEFREE Modulation of the inflammatory response through targeted inhibition of the enzyme COX-2 by means of CBX reduces TRBDD and augments and accelerates treatment response in an efficacious and safe manner. 31630035 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.020 Biomarker disease BEFREE A search strategy was developed using the terms: "Bipolar disorder" or "Bipolar mania" or "Bipolar depression" or "Bipolar mixed" or "Bipolar euthymic" and "Celecoxib" or "Cyclooxygenase-2 inhibitors" or "Cox-2 inhibitors" as text words and Medical Subject Headings (i.e., MeSH and EMTREE) and searched. 30398124 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.200 Biomarker disease RGD The genetic association database. 15118671 2004
Entrez Id: 5428
Gene Symbol: POLG
POLG 		0.200 Biomarker disease MGD
Entrez Id: 815
Gene Symbol: CAMK2A
CAMK2A 		0.200 Biomarker disease MGD
Entrez Id: 478
Gene Symbol: ATP1A3
ATP1A3 		0.200 Biomarker disease MGD
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.230 GeneticVariation disease BEFREE CLOCK gene variants associated with the discrepancy between subjective and objective severity in bipolar depression. 27992853 2017
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.230 GeneticVariation disease BEFREE Effects of CLOCK gene variants and early stress on hopelessness and suicide in bipolar depression. 26204460 2015
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.230 GeneticVariation disease BEFREE Influence of CLOCK gene polymorphism on circadian mood fluctuation and illness recurrence in bipolar depression. 14582141 2003
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK 		0.230 Biomarker disease MGD
Entrez Id: 5091
Gene Symbol: PC
PC 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 57519
Gene Symbol: STARD9
STARD9 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 51177
Gene Symbol: PLEKHO1
PLEKHO1 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 51650
Gene Symbol: MRPS33
MRPS33 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 22941
Gene Symbol: SHANK2
SHANK2 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 6733
Gene Symbol: SRPK2
SRPK2 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 9881
Gene Symbol: TRANK1
TRANK1 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 2903
Gene Symbol: GRIN2A
GRIN2A 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 9415
Gene Symbol: FADS2
FADS2 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 55690
Gene Symbol: PACS1
PACS1 		0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019