Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 815
Gene Symbol: CAMK2A
CAMK2A
0.200 Biomarker disease MGD
Entrez Id: 961
Gene Symbol: CD47
CD47
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK
0.230 GeneticVariation disease BEFREE Effects of CLOCK gene variants and early stress on hopelessness and suicide in bipolar depression. 26204460 2015
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK
0.230 Biomarker disease MGD
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK
0.230 GeneticVariation disease BEFREE CLOCK gene variants associated with the discrepancy between subjective and objective severity in bipolar depression. 27992853 2017
Entrez Id: 9575
Gene Symbol: CLOCK
CLOCK
0.230 GeneticVariation disease BEFREE Influence of CLOCK gene polymorphism on circadian mood fluctuation and illness recurrence in bipolar depression. 14582141 2003
Entrez Id: 1312
Gene Symbol: COMT
COMT
0.510 Biomarker disease PSYGENET In this study we examined the expression levels of COMT mRNA using quantitative RT-PCR in 60 post mortem cerebellum samples derived from individuals with schizophrenia, bipolar disorder, depression, and no history of psychopathology. 16483362 2006
Entrez Id: 1312
Gene Symbol: COMT
COMT
0.510 GeneticVariation disease BEFREE Associations have also been reported between the catechol-O-methyltransferase (COMT) gene and both OCD and bipolar depression. 12815746 2003
Entrez Id: 1312
Gene Symbol: COMT
COMT
0.510 Biomarker disease PSYGENET Associations have also been reported between the catechol-O-methyltransferase (COMT) gene and both OCD and bipolar depression. 12815746 2003
Entrez Id: 1312
Gene Symbol: COMT
COMT
0.510 Biomarker disease CTD_human Catechol o-methyltransferase, serotonin transporter, and tryptophan hydroxylase gene polymorphisms in bipolar disorder patients with and without comorbid panic disorder. 11772685 2002
Entrez Id: 10815
Gene Symbol: CPLX1
CPLX1
0.300 Biomarker disease CTD_human Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. 14708030 2004
Entrez Id: 10814
Gene Symbol: CPLX2
CPLX2
0.300 Biomarker disease CTD_human Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. 14708030 2004
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.010 Biomarker disease BEFREE C-reactive protein and response to lurasidone in patients with bipolar depression. 30102967 2018
Entrez Id: 1523
Gene Symbol: CUX1
CUX1
0.010 Biomarker disease BEFREE Here, we measured serum levels of tPA, plasminogen activator inhibitor-1 (PAI-1), BDNF, precursor-BDNF (proBDNF), tropomyosin-related kinase B (TrkB) and neurotrophin receptor p75 (p75NTR) in patients with paranoid schizophrenia (SZ, n = 34), MDD (n = 30), bipolar mania (BM, n = 30), bipolar depression (BD, n = 22), panic disorder (PD, n = 30), and healthy controls (HCs, n = 30) by Enzyme-linked immunosorbent assay kits. 28761093 2017
Entrez Id: 27185
Gene Symbol: DISC1
DISC1
0.310 Biomarker disease PSYGENET Disrupted in Schizophrenia 1 (DISC1) is a key susceptibility gene implicated in major mental illnesses, such as schizophrenia, depression, bipolar disorder and autism, but the link between this protein and the pathology of these diseases remains unclear. 22291444 2012
Entrez Id: 27185
Gene Symbol: DISC1
DISC1
0.310 Biomarker disease BEFREE Disrupted in Schizophrenia 1 (DISC1) is a key susceptibility gene implicated in major mental illnesses, such as schizophrenia, depression, bipolar disorder and autism, but the link between this protein and the pathology of these diseases remains unclear. 22291444 2012
Entrez Id: 85458
Gene Symbol: DIXDC1
DIXDC1
0.300 Biomarker disease CTD_human DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling. 27752079 2018
Entrez Id: 1812
Gene Symbol: DRD1
DRD1
0.300 Biomarker disease CTD_human Dopamine D1 receptor gene polymorphism is associated with prophylactic lithium response in bipolar disorder. 19153942 2009
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.010 GeneticVariation disease BEFREE Dopamine receptor D2 and D3 gene variants are not associated with the antidepressant effect of total sleep deprivation in bipolar depression. 12834818 2003
Entrez Id: 1816
Gene Symbol: DRD5
DRD5
0.300 Biomarker disease CTD_human Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. 14708030 2004
Entrez Id: 100379198
Gene Symbol: ECT
ECT
0.010 Biomarker disease BEFREE This is the first report in the literature of a patient undergoing ECT for bipolar depression with recent activation of Inspire hypoglossal nerve stimulator who had no disruption in the function of his implanted device. 29703415 2018
Entrez Id: 2022
Gene Symbol: ENG
ENG
0.010 Biomarker disease BEFREE Further validation and investigation are required to illuminate the roles of B2RAN2 and ENG in MDD and BP. 28910601 2017
Entrez Id: 9415
Gene Symbol: FADS2
FADS2
0.300 Biomarker disease CTD_human Genome-wide association study identifies 30 loci associated with bipolar disorder. 31043756 2019
Entrez Id: 56975
Gene Symbol: FAM20C
FAM20C
0.010 Biomarker disease BEFREE These neurodegenerative disorders like Alzeimers, Parkinsons disease and neuropsychiatric disorders such as schizophrenia, bipolar, depression are caused due to the decline in physiological and psychological functions caused by ROS and RNS. 30644343 2018
Entrez Id: 26291
Gene Symbol: FGF21
FGF21
0.010 Biomarker disease BEFREE In this study, we investigated whether fibroblast growth factor-21 (FGF21) was associated with metabolic effects and treatment response in depressed bipolar disorder patients. 29618013 2018