Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 641
Gene Symbol: BLM
BLM 		0.110 Biomarker group HPO
Entrez Id: 6391
Gene Symbol: SDHC
SDHC 		0.100 Biomarker group HPO
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		0.100 Biomarker group HPO
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		0.100 Biomarker group HPO
Entrez Id: 2191
Gene Symbol: FAP
FAP 		0.010 Biomarker group BEFREE FAP coli patients treated by prophylactic surgery are now known to be at risk of developing adenomas anywhere in the intestine and many affected patients later die from upper gastrointestinal tumors. 10604226 1999
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2 		0.010 AlteredExpression group BEFREE EphB2, a member of the Eph receptor protein-tyrosine kinase family, is overexpressed in several human gastrointestinal tumors. 11166921 2001
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		0.020 Biomarker group BEFREE hMLH1, the human MutL homologue, has been linked to microsatellite instability (MSI) in gastrointestinal tumors. 14601090 2003
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		0.010 Biomarker group BEFREE Pai-1 deficiency reduced the number of aggressive fibromatosis tumors formed, but not the number of gastrointestinal tumors. 15674349 2005
Entrez Id: 466
Gene Symbol: ATF1
ATF1 		0.010 Biomarker group BEFREE EWS-ATF1 fusion transcripts in gastrointestinal tumors previously diagnosed as malignant melanoma. 15712185 2005
Entrez Id: 960
Gene Symbol: CD44
CD44 		0.020 AlteredExpression group BEFREE CD44 expression level is linked to the cell cycle in gastrointestinal tumor cells, which in turn leads to cell cycle dependent alterations of their adhesion behaviour to endothelium. 16419149 2005
Entrez Id: 5395
Gene Symbol: PMS2
PMS2 		0.020 GeneticVariation group BEFREE PMS2 mutations-and perhaps other homozygous mismatch repair mutations-should be considered in any patient presenting with multiple gastrointestinal tumors, since our patient could not be distinguished clinically from cases with attenuated familial adenomatous polyposis or MUTYH-associated polyposis. 17258725 2007
Entrez Id: 5754
Gene Symbol: PTK7
PTK7 		0.010 Biomarker group BEFREE PTK7 and SEMA6A were expressed in undifferentiated embryonic stem (ES) cells, SEMA6A in endodermal progenitors, CELSR1, VANGL1 and PTK7 in gastrointestinal tumors. 17671748 2007
Entrez Id: 79816
Gene Symbol: TLE6
TLE6 		0.010 Biomarker group BEFREE Tle6-like;TLE6D directly interact with the gastrointestinal tumor suppressor RUNX3 and antagonize RUNX3 target transactivation. 18551179 2008
Entrez Id: 1950
Gene Symbol: EGF
EGF 		0.030 AlteredExpression group BEFREE Epidermal growth factor (EGF) has an important role in the protection and repair of mucosal damage, and non-physiologic levels are associated with gastrointestinal tumors. 22129558 2012
Entrez Id: 2520
Gene Symbol: GAST
GAST 		0.010 Biomarker group BEFREE Gastrin and its precursors have been shown to promote mitogenesis and angiogenesis in gastrointestinal tumors. 22593272 2012
Entrez Id: 2273
Gene Symbol: FHL1
FHL1 		0.010 Biomarker group BEFREE FHL1 on chromosome X is a single-hit gastrointestinal tumor-suppressor gene and contributes to the formation of an epigenetic field defect. 22689052 2013
Entrez Id: 79581
Gene Symbol: SLC52A2
SLC52A2 		0.010 Biomarker group BEFREE PAR-1 has been involved in inflammation of the gastrointestinal tract, tumour cell growth and invasion of gastric carcinoma cells. 22993310 2012
Entrez Id: 145624
Gene Symbol: PWAR1
PWAR1 		0.010 Biomarker group BEFREE PAR-1 has been involved in inflammation of the gastrointestinal tract, tumour cell growth and invasion of gastric carcinoma cells. 22993310 2012
Entrez Id: 2149
Gene Symbol: F2R
F2R 		0.010 Biomarker group BEFREE PAR-1 has been involved in inflammation of the gastrointestinal tract, tumour cell growth and invasion of gastric carcinoma cells. 22993310 2012
Entrez Id: 8856
Gene Symbol: NR1I2
NR1I2 		0.010 Biomarker group BEFREE PAR-1 has been involved in inflammation of the gastrointestinal tract, tumour cell growth and invasion of gastric carcinoma cells. 22993310 2012
Entrez Id: 2011
Gene Symbol: MARK2
MARK2 		0.010 Biomarker group BEFREE PAR-1 has been involved in inflammation of the gastrointestinal tract, tumour cell growth and invasion of gastric carcinoma cells. 22993310 2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.010 AlteredExpression group BEFREE IL-1β is a pleiotropic pro-inflammatory cytokine and its up-regulation is closely associated with various cancers including gastrointestinal tumors. 23174018 2012
Entrez Id: 1015
Gene Symbol: CDH17
CDH17 		0.010 Biomarker group BEFREE CDH17 may be especially valuable when gastrointestinal tumors are suspected in cancers of unknown primary. 28029907 2017
Entrez Id: 551
Gene Symbol: AVP
AVP 		0.010 Biomarker group BEFREE AVP receptors are present in human lung, breast, pancreatic, colorectal, and gastrointestinal tumors. 28194370 2017
Entrez Id: 406931
Gene Symbol: MIR139
MIR139 		0.010 Biomarker group BEFREE MiR-139 in digestive system tumor diagnosis and detection: Bioinformatics and meta-analysis. 29883634 2018