×
Entrez Id: 124626
Gene Symbol: ZPBP2
ZPBP2
0.010
AlteredExpression
group
BEFREE
The susceptibility allele was also associated with the increased expression of GSDMA (P = 1.6 × 10(-4)) and LRRC3C (P = 7.8 × 10(-6)) in colon tissue from individuals without IBD and with the reduced expression of PGAP3 (IBD ; P = 2.0 × 10(-3)) and ZPBP2 (Crohn's disease; P = 7.7 × 10(-4)) in noninflamed ileum.
26484354 2015
×
Entrez Id: 128611
Gene Symbol: ZNF831
ZNF831
0.100
GeneticVariation
group
GWASCAT
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
23128233 2012
×
Entrez Id: 128611
Gene Symbol: ZNF831
ZNF831
0.100
GeneticVariation
group
GWASCAT
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
26192919 2015
×
Entrez Id: 128611
Gene Symbol: ZNF831
ZNF831
0.100
GeneticVariation
group
GWASCAT
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.
28067908 2017
×
Entrez Id: 128611
Gene Symbol: ZNF831
ZNF831
0.100
GeneticVariation
group
GWASDB
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
23128233 2012
×
Entrez Id: 57862
Gene Symbol: ZNF410
ZNF410
0.010
GeneticVariation
group
BEFREE
The objective of this study was to assess the association of VDR gene polymorphisms (Apa I , Taq I, Bsm I, Fok I) with IBD in Iran.
18752562 2008
ZNF300P1
0.100
GeneticVariation
group
GWASCAT
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
26192919 2015
×
Entrez Id: 91975
Gene Symbol: ZNF300
ZNF300
0.100
GeneticVariation
group
GWASCAT
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.
28067908 2017
×
Entrez Id: 91975
Gene Symbol: ZNF300
ZNF300
0.100
GeneticVariation
group
GWASCAT
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
23128233 2012
×
Entrez Id: 91975
Gene Symbol: ZNF300
ZNF300
0.100
GeneticVariation
group
GWASDB
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
23128233 2012
×
Entrez Id: 23528
Gene Symbol: ZNF281
ZNF281
0.010
AlteredExpression
group
BEFREE
<b>Conclusions:</b> The identification of transcription factor ZNF281 as a novel player of intestinal inflammation and fibrosis allows a deeper comprehension of the pathogenetic mechanisms underlying inflammatory bowel disease (IBD ) and provide a new target for their cure.
30619271 2018
×
Entrez Id: 7692
Gene Symbol: ZNF133
ZNF133
0.010
Biomarker
group
BEFREE
ZNF133 is associated with infliximab responsiveness in patients with inflammatory bowel diseases .30851117 2019
×
Entrez Id: 57178
Gene Symbol: ZMIZ1
ZMIZ1
0.120
GeneticVariation
group
GWASDB
Common variants at five new loci associated with early-onset inflammatory bowel disease.
19915574 2009
×
Entrez Id: 57178
Gene Symbol: ZMIZ1
ZMIZ1
0.120
Biomarker
group
BEFREE
Most importantly, we found that ZMIZ1 expression was markedly higher in both IBD patients and mice with experimentally induced colitis, suggesting that ZMIZ1 plays important roles in the pathogenesis of IBD .
28456797 2017
×
Entrez Id: 57178
Gene Symbol: ZMIZ1
ZMIZ1
0.120
GeneticVariation
group
GWASCAT
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
26192919 2015
×
Entrez Id: 57178
Gene Symbol: ZMIZ1
ZMIZ1
0.120
GeneticVariation
group
BEFREE
Consistent with epidemiologic predictions, many IBD -associated loci demonstrate genome-wide significant associations to both CD and UC, notably, genes whose products function in the interleukin-23 pathway, and transcription factors, including NK2 transcription factor related, locus 3 (NKX2-3), SMAD3, STAT3, ZMIZ1 , and c-REL.
21530736 2011
×
Entrez Id: 57178
Gene Symbol: ZMIZ1
ZMIZ1
0.120
GeneticVariation
group
GWASCAT
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
23128233 2012
×
Entrez Id: 57178
Gene Symbol: ZMIZ1
ZMIZ1
0.120
GeneticVariation
group
GWASDB
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
23128233 2012
×
Entrez Id: 57178
Gene Symbol: ZMIZ1
ZMIZ1
0.120
GeneticVariation
group
GWASCAT
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease.
28067908 2017
×
Entrez Id: 57178
Gene Symbol: ZMIZ1
ZMIZ1
0.120
GeneticVariation
group
GWASCAT
Common variants at five new loci associated with early-onset inflammatory bowel disease.
19915574 2009
×
Entrez Id: 84619
Gene Symbol: ZGPAT
ZGPAT
0.100
GeneticVariation
group
GWASCAT
Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.
18758464 2008
×
Entrez Id: 84619
Gene Symbol: ZGPAT
ZGPAT
0.100
GeneticVariation
group
GWASCAT
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
23128233 2012
×
Entrez Id: 84619
Gene Symbol: ZGPAT
ZGPAT
0.100
GeneticVariation
group
GWASDB
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
23128233 2012
×
Entrez Id: 84619
Gene Symbol: ZGPAT
ZGPAT
0.100
GeneticVariation
group
GWASDB
Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.
18758464 2008
×
Entrez Id: 146198
Gene Symbol: ZFP90
ZFP90
0.010
GeneticVariation
group
BEFREE
We identified genes that might be truly causative, but GWAS might have failed to identify for 148 out of the GWAS-identified SNPs; for example, TUFM (P = 3.3E-48) was identified for inflammatory bowel disease (early onset); ZFP90 (P = 4.4E-34) for ulcerative colitis; and IDUA (P = 2.2E-11) for Parkinson's disease.
24956270 2014